Title: | Serological methods for detection of infection with shrew-borne hantaviruses : Thottapalayam, Seewis, Altai, and Asama viruses |
Authors: | Wei, Zhouoxing Browse this author |
Shimizu, Kenta Browse this author →KAKEN DB |
Nishigami, Kumpei Browse this author |
Tsuda, Yoshimi Browse this author |
Sarathukumara, Yomani Browse this author |
Muthusinghe, Devinda S. Browse this author |
Gamage, Chandika D. Browse this author |
Granathne, Lishanta Browse this author |
Lokupathirage, Sithumini M. W. Browse this author |
Nanayakkara, Nishanta Browse this author |
Arikawa, Jiro Browse this author →KAKEN DB |
Kikuchi, Fuka Browse this author |
Tanaka-Taya, Keiko Browse this author |
Suzuki, Motoi Browse this author |
Morikawa, Shigeru Browse this author →KAKEN DB |
Arai, Satoru Browse this author →KAKEN DB |
Yoshimatsu, Kumiko Browse this author →KAKEN DB |
Issue Date: | Jan-2021 |
Publisher: | Springer |
Journal Title: | Archives of virology |
Volume: | 166 |
Start Page: | 275 |
End Page: | 280 |
Publisher DOI: | 10.1007/s00705-020-04873-3 |
Abstract: | The infectivity of shrew-borne hantaviruses to humans is still unclear because of the lack of a serodiagnosis method for these viruses. In this study, we prepared recombinant nucleocapsid (rN) proteins of Seewis orthohantavirus, Altai orthohantavirus (ALTV), Thottapalayam thottimvirus (TPMV), and Asama orthohantavirus. Using monospecific rabbit sera, no antigenic cross-reactivity was observed. In a serosurvey of 104 samples from renal patients and 271 samples from heathy controls from Sri Lanka, one patient serum and two healthy control sera reacted with rN proteins of ALTV and TPMV, respectively. The novel assays should be applied to investigate potential infectivity of shrew-borne hantaviruses to humans. |
Rights: | This is a post-peer-review, pre-copyedit version of an article published in Archives of Virology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00705-020-04873-3 |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/83794 |
Appears in Collections: | 遺伝子病制御研究所 (Institute for Genetic Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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