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Association between pre-pregnancy body mass index and gestational weight gain and perinatal outcomes in pregnant women diagnosed with gestational diabetes mellitus : The Japan Environment and Children's Study

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Title: Association between pre-pregnancy body mass index and gestational weight gain and perinatal outcomes in pregnant women diagnosed with gestational diabetes mellitus : The Japan Environment and Children's Study
Authors: Saito, Yoshihiro Browse this author
Kobayashi, Sumitaka Browse this author →KAKEN DB
Ikeda-Araki, Atsuko Browse this author →KAKEN DB
Ito, Sachiko Browse this author →KAKEN DB
Miyashita, Chihiro Browse this author →KAKEN DB
Kimura, Takashi Browse this author →KAKEN DB
Hirata, Takumi Browse this author →KAKEN DB
Tamakoshi, Akiko Browse this author →KAKEN DB
Mayama, Michinori Browse this author
Noshiro, Kiwamu Browse this author
Nakagawa, Kinuko Browse this author
Umazume, Takeshi Browse this author →KAKEN DB
Chiba, Kentaro Browse this author
Kawaguchi, Satoshi Browse this author
Morikawa, Mamoru Browse this author →KAKEN DB
Cho, Kazutoshi Browse this author →KAKEN DB
Watari, Hidemichi Browse this author →KAKEN DB
Ito, Yoshiya Browse this author →KAKEN DB
Saijo, Yasuaki Browse this author →KAKEN DB
Kishi, Reiko Browse this author →KAKEN DB
Keywords: Body mass index
Gestational diabetes mellitus
Gestational weight gain
Issue Date: 28-Jan-2022
Publisher: John Wiley & Sons
Journal Title: Journal of diabetes investigation
Volume: 13
Issue: 5
Start Page: 889
End Page: 899
Publisher DOI: 10.1111/jdi.13723
Abstract: Aims/Introduction We investigated the association between gestational diabetes mellitus (GDM) and perinatal outcomes stratified by pre-pregnancy body mass index (BMI) and/or gestational weight gain (GWG). Materials and Methods Data from the national birth cohort in the Japan Environment and Children's Study from 2011 to 2014 (n = 85,228) were used. Japan uses the GDM guidelines of the International Association of Diabetes and Pregnancy Study Groups. The odds ratios (ORs) of perinatal outcomes were compared between women with and those without GDM. Results The OR (95% confidence interval) of having a small for gestational age infant in the GDM group with a pre-pregnancy BMI of >= 25.0 kg/m(2) and insufficient GWG (<2.75 kg) was 1.78 (1.02-3.12). The OR of having a large for gestational age infant of the same BMI group with excessive GWG (>7.25 kg) was 2.04 (1.56-2.67). The OR of hypertensive disorders of pregnancy was higher in women with a BMI >= 18.5 kg/m(2) in the GDM group than in the non-GDM group. Conclusions Large for gestational age and hypertensive disorders of pregnancy were associated with pre-pregnancy BMI and GWG in either normal weight or overweight/obese women, and the relationship was strengthened when GDM was present. Women with GDM and a BMI of >= 25.0 kg/m(2) are at risk of having small for gestational age and large for gestational age infants depending on GWG.
Type: article
URI: http://hdl.handle.net/2115/83941
Appears in Collections:環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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