Title: | Association between pre-pregnancy body mass index and gestational weight gain and perinatal outcomes in pregnant women diagnosed with gestational diabetes mellitus : The Japan Environment and Children's Study |
Authors: | Saito, Yoshihiro Browse this author |
Kobayashi, Sumitaka Browse this author →KAKEN DB |
Ikeda-Araki, Atsuko Browse this author →KAKEN DB |
Ito, Sachiko Browse this author →KAKEN DB |
Miyashita, Chihiro Browse this author →KAKEN DB |
Kimura, Takashi Browse this author →KAKEN DB |
Hirata, Takumi Browse this author →KAKEN DB |
Tamakoshi, Akiko Browse this author →KAKEN DB |
Mayama, Michinori Browse this author |
Noshiro, Kiwamu Browse this author |
Nakagawa, Kinuko Browse this author |
Umazume, Takeshi Browse this author →KAKEN DB |
Chiba, Kentaro Browse this author |
Kawaguchi, Satoshi Browse this author |
Morikawa, Mamoru Browse this author →KAKEN DB |
Cho, Kazutoshi Browse this author →KAKEN DB |
Watari, Hidemichi Browse this author →KAKEN DB |
Ito, Yoshiya Browse this author →KAKEN DB |
Saijo, Yasuaki Browse this author →KAKEN DB |
Kishi, Reiko Browse this author →KAKEN DB |
Keywords: | Body mass index |
Gestational diabetes mellitus |
Gestational weight gain |
Issue Date: | 28-Jan-2022 |
Publisher: | John Wiley & Sons |
Journal Title: | Journal of diabetes investigation |
Publisher DOI: | 10.1111/jdi.13723 |
Abstract: | Aims/Introduction We investigated the association between gestational diabetes mellitus (GDM) and perinatal outcomes stratified by pre-pregnancy body mass index (BMI) and/or gestational weight gain (GWG). Materials and Methods Data from the national birth cohort in the Japan Environment and Children's Study from 2011 to 2014 (n = 85,228) were used. Japan uses the GDM guidelines of the International Association of Diabetes and Pregnancy Study Groups. The odds ratios (ORs) of perinatal outcomes were compared between women with and those without GDM. Results The OR (95% confidence interval) of having a small for gestational age infant in the GDM group with a pre-pregnancy BMI of >= 25.0 kg/m(2) and insufficient GWG (<2.75 kg) was 1.78 (1.02-3.12). The OR of having a large for gestational age infant of the same BMI group with excessive GWG (>7.25 kg) was 2.04 (1.56-2.67). The OR of hypertensive disorders of pregnancy was higher in women with a BMI >= 18.5 kg/m(2) in the GDM group than in the non-GDM group. Conclusions Large for gestational age and hypertensive disorders of pregnancy were associated with pre-pregnancy BMI and GWG in either normal weight or overweight/obese women, and the relationship was strengthened when GDM was present. Women with GDM and a BMI of >= 25.0 kg/m(2) are at risk of having small for gestational age and large for gestational age infants depending on GWG. |
Type: | article |
URI: | http://hdl.handle.net/2115/83941 |
Appears in Collections: | 環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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