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Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure

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Title: Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
Authors: Fujii, Shintaro Browse this author
Horiuchi, Kazuhiro Browse this author
Oshima, Yuki Browse this author
Eguchi, Katsuki Browse this author
Nagai, Azusa Browse this author
Iwata, Ikuko Browse this author
Matsushima, Masaaki Browse this author
Yabe, Ichiro Browse this author →KAKEN DB
Keywords: anti-mitochondrial antibodies
inflammatory myopathy
type II respiratory failure
immune-mediated necrotizing myopathy
Issue Date: 1-Dec-2021
Publisher: 日本内科学会(The Japanese Society of Internal Medicine)
Journal Title: Internal medicine
Volume: 60
Issue: 23
Start Page: 3801
End Page: 3804
Publisher DOI: 10.2169/internalmedicine.7448-21
Abstract: A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. After treatment with corticosteroids and noninvasive positive pressure ventilation, her symptoms improved. If a diagnosis of type II respiratory failure is difficult, inflammatory myopathy associated with AMA should be considered as a differential diagnosis.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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