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Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure
Title: | Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure |
Authors: | Fujii, Shintaro Browse this author | Horiuchi, Kazuhiro Browse this author | Oshima, Yuki Browse this author | Eguchi, Katsuki Browse this author | Nagai, Azusa Browse this author | Iwata, Ikuko Browse this author | Matsushima, Masaaki Browse this author | Yabe, Ichiro Browse this author →KAKEN DB |
Keywords: | anti-mitochondrial antibodies | inflammatory myopathy | type II respiratory failure | immune-mediated necrotizing myopathy | immunotherapy |
Issue Date: | 1-Dec-2021 |
Publisher: | 日本内科学会(The Japanese Society of Internal Medicine) |
Journal Title: | Internal medicine |
Volume: | 60 |
Issue: | 23 |
Start Page: | 3801 |
End Page: | 3804 |
Publisher DOI: | 10.2169/internalmedicine.7448-21 |
Abstract: | A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. After treatment with corticosteroids and noninvasive positive pressure ventilation, her symptoms improved. If a diagnosis of type II respiratory failure is difficult, inflammatory myopathy associated with AMA should be considered as a differential diagnosis. |
Type: | article |
URI: | http://hdl.handle.net/2115/83955 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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