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Endonasal endoscopic surgery for sinonasal squamous cell carcinoma from an oncological perspective

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Title: Endonasal endoscopic surgery for sinonasal squamous cell carcinoma from an oncological perspective
Authors: Homma, Akihiro Browse this author →KAKEN DB
Nakamaru, Yuji Browse this author
Lund, Valerie J. Browse this author
Hanna, Ehab Y. Browse this author
Kowalski, Luiz Paulo Browse this author
Toledo, Ronaldo Nunes Browse this author
Makitie, Antti A. Browse this author
Rodrigo, Juan Pablo Browse this author
Rinaldo, Alessandra Browse this author
Snyderman, Carl H. Browse this author
Ferlito, Alfio Browse this author
Keywords: Squamous cell carcinoma
Endonasal endoscopic surgery
Nasal cavity
Paranasal sinus
Issue Date: Feb-2021
Publisher: Elsevier
Journal Title: Auris nasus larynx
Volume: 48
Issue: 1
Start Page: 41
End Page: 49
Publisher DOI: 10.1016/j.anl.2020.11.018
Abstract: Endonasal endoscopic surgery (EES) has been applied to the management of sinonasal (SN) tumors based on recent advances in endoscopic surgical techniques and technologies over the past three decades. EES has been mainly indicated for benign tumors and less aggressive malignant tumors. Notwithstanding this, EES has been gradually adopted for squamous cell carcinoma (SCC), which is the most common histology among SN malignancies. However, an analysis of the outcomes of EES for patients with SCC is difficult because most articles included SCC a wide range of different tumor histologies. Therefore, we herein review and clarify the current status of EES focusing on SCC from an oncological perspective. The oncologic outcomes and the ability to achieve a histologically complete resection are similar between endoscopic and open approaches in highly selected patients with SN-SCC. Surgical complications associated with EES are likely similar for SN-SCC compared to other sinonasal malignancies. The indications for a minimally invasive approach such as EES in the management of patients with SN-SCC should be stricter than those for less aggressive malignant tumors because of the aggressive nature of SCC. Also, it is important to achieve negative surgical margins with EES in patients with SCC. We believe that the indications for EES for SN-SCC are widening due to advances in diagnostic imaging, and endoscopic surgical techniques and technologies. However, while expanding the indications for EES for SN-SCC we must carefully confirm that the outcomes support this strategy. (c) 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.
Rights: ©2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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