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Long-term survival after repetitive lymphadenectomy for nodal recurrence of pancreatic neuroendocrine neoplasms : a report of two cases

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Title: Long-term survival after repetitive lymphadenectomy for nodal recurrence of pancreatic neuroendocrine neoplasms : a report of two cases
Authors: Hane, Yuma Browse this author
Tsuchikawa, Takahiro Browse this author →KAKEN DB
Takeuchi, Satoshi Browse this author
Tanaka, Kimitaka Browse this author →KAKEN DB
Nakanishi, Yoshitsugu Browse this author →KAKEN DB
Asano, Toshimichi Browse this author →KAKEN DB
Noji, Takehiro Browse this author →KAKEN DB
Kurashima, Yo Browse this author
Ebihara, Yuma Browse this author
Murakami, Soichi Browse this author →KAKEN DB
Nakamura, Toru Browse this author
Okamura, Keisuke Browse this author
Shichinohe, Toshiaki Browse this author →KAKEN DB
Hirano, Satoshi Browse this author →KAKEN DB
Issue Date: 13-Oct-2021
Publisher: Oxford University Press
Journal Title: Journal of surgical case reports
Volume: 2021
Issue: 10
Start Page: rjab446
Publisher DOI: 10.1093/jscr/rjab446
Abstract: Pancreatic neuroendocrine neoplasms (PNENs) are rare, but their incidence has increased in recent years. Curative surgery is recommended in several global guidelines for resectable PNENs. Lymph node recurrence after R0 resection for PNENs is infrequent, and global guidelines recommend surgical resection for recurrence, if resectable. However, data on the prognosis after surgical resection for nodal recurrence of PNENs are limited. We herein report two cases in which long-term survival was achieved after repetitive lymphadenectomy for nodal recurrence of PNENs. In both cases, the pathological findings for primary PNEN showed well-differentiated neuroendocrine neoplasms and R0 resection was successfully performed. The Ki-67 index increased with each resection in both cases. Both patients showed long-term survival (10 and 14 years, respectively). Repetitive lymphadenectomy for nodal recurrence of PNENs may improve patient prognosis.
Type: article
URI: http://hdl.handle.net/2115/84689
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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