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Integral radiation dose to normal structures with conformal external beam radiation

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タイトル: Integral radiation dose to normal structures with conformal external beam radiation
その他のタイトル: Normal Integral dose of IMRT and tomotherapy
著者: Aoyama, Hidefumi 著作を一覧する
Westerly, David Clark 著作を一覧する
Mackie, Thomas Rockwell 著作を一覧する
Olivera, Gustavo H. 著作を一覧する
Bentzen, Soren M. 著作を一覧する
Patel, Rakesh R. 著作を一覧する
Jaradat, Hazim 著作を一覧する
Tome, Wolfgang A. 著作を一覧する
Ritter, Mark A. 著作を一覧する
Mehta, Minesh P. 著作を一覧する
キーワード: Radiation
IMRT
Tomotherapy
Prostrate cancer
Integral dose
発行日: 2006年 3月
出版者: Elsevier
誌名: International Journal of Radiation Oncology Biology Physics
巻: 64
号: 3
開始ページ: 962
終了ページ: 967
出版社 DOI: 10.1016/j.ijrobp.2005.11.005
抄録: Background: This study was designed to evaluate the integral dose (ID) received by normal tissue from intensity modulated radiotherapy (IMRT) for prostate cancer. Materials and Methods: Twenty-five radiation treatment plans, including MRT using a conventional linac with both 6 (6MV-IMRT) and 20 MV (20MV-IMRT) as well as 3DCRT using 6 (6MV-3DCRT) and 20 MV (20MV-3DCRT), and IMRT using tomotherapy (6MV) (Tomo-IMRT), were created for five patients with localized prostate cancer. The ID (mean dose X tissue volume) received by normal tissue (NTID) was calculated from dose-volume histograms. Results: 6MV-IMRT resulted in 5.0% lower NTID than 6MV-3DCRT; 20MV beam plans resulted in 7.7-11.2% lower NTID than 6 MV-3DCRT. Tomo-IMRT NTID was comparable to 6 MV-IMRT. Compared to 6MV-3DCRT, 6MV-IMRT reduced IDs to the rectal wall and penile bulb by 6.1% and 2.7%, respectively. Tomo-IMRT further reduced these IDs by 11.9% and 16.5%, respectively. 20MV did not reduce IDs to those structures. Conclusions: The difference of NTID between 3DCRT and IMRT is small. 20MV plans somewhat reduced NTID compared to 6MV plans. The advantage of tomotherapy over conventional IMRT and 3DCRT for localized prostate cancer was demonstrated in regard to dose sparing of rectal wall and penile bulb without increasing NTID.
Relation (URI): http://www.sciencedirect.com/science/journal/03603016
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/8470
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 青山 英史

 

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