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A drainage strategy for postoperative pancreatic fistula after left-sided pancreatectomy based on the wall status of collected fluid

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/85244

Title: A drainage strategy for postoperative pancreatic fistula after left-sided pancreatectomy based on the wall status of collected fluid
Authors: Kuwatani, Masaki Browse this author →KAKEN DB
Imamura, Masafumi Browse this author →KAKEN DB
Hayashi, Tsuyoshi Browse this author →KAKEN DB
Yoshida, Makoto Browse this author →KAKEN DB
Kimura, Yasutoshi Browse this author →KAKEN DB
Asano, Toshimichi Browse this author →KAKEN DB
Nakamura, Toru Browse this author →KAKEN DB
Motoya, Masayo Browse this author →KAKEN DB
Yoshida, Makoto Browse this author →KAKEN DB
Noji, Takehiro Browse this author →KAKEN DB
Okamura, Keisuke Browse this author →KAKEN DB
Takahashi, Kuniyuki Browse this author
Katanuma, Akio Browse this author
Hirano, Satoshi Browse this author →KAKEN DB
Keywords: Pancreatic fistula
Endoscopic ultrasonography
Percutaneous drainage
Pancreatectomy
Resection
Issue Date: May-2021
Publisher: Springer
Journal Title: Langenbeck's archives of surgery
Volume: 406
Issue: 3
Start Page: 743
End Page: 751
Publisher DOI: 10.1007/s00423-020-02067-8
Abstract: Purpose Postoperative pancreatic fistula (POPF) after pancreatectomy is one of the severe postoperative adverse events. We aimed to clarify the outcomes of a strategy for POPF after left-sided pancreatectomy with one-step endoscopic ultrasonography-guided drainage (EUSD) and percutaneous drainage (PCD) based on the wall status of collected fluid. Methods From January 2012 to September 2017, 90 of 336 patients developed grade B/C POPF and were retrospectively analyzed. Primary outcome measures were the technical and clinical success and resolution rates. Secondary outcome measures were time from surgery to intervention, and time from intervention to discharge/resolution or stent/tube removal and adverse events. Results Seventeen patients underwent EUSD and 73 patients underwent PCD for POPF. The technical success rates were 100% in both the EUSD and PCD groups. The clinical success and resolution rates in the EUSD group were 100%, while those in the PCD group were 98.6%. The time from surgery to intervention was significantly longer in the EUSD group than in the PCD group (20 vs. 11 days, p < 0.001). The time from intervention to discharge/resolution was significantly shorter in the EUSD group than in the PCD group (11 vs. 22 days, p < 0.001/10 vs. 20 days, p < 0.001). The time from intervention to stent/tube removal was significantly shorter in the PCD group than in the EUSD group (20.5 vs. 873 days, p < 0.001). Adverse event rates were similar in the two groups (11.8% vs. 5.5%). Conclusion A drainage strategy for POPF based on the wall status of collected fluid is appropriate.
Rights: This is a post-peer-review, pre-copyedit version of an article published in Langenbeck's archives of surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00423-020-02067-8
Type: article (author version)
URI: http://hdl.handle.net/2115/85244
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 桒谷 将城

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