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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Peer-reviewed Journal Articles, etc >
Human Health Risk Assessment from Lead Exposure through Consumption of Raw Cow Milk from Free-Range Cattle Reared in the Vicinity of a Lead-Zinc Mine in Kabwe
| Title: | Human Health Risk Assessment from Lead Exposure through Consumption of Raw Cow Milk from Free-Range Cattle Reared in the Vicinity of a Lead-Zinc Mine in Kabwe |
| Authors: | Zyambo, Golden Browse this author | | Yabe, John Browse this author | | Muzandu, Kaampwe Browse this author | | M'kandawire, Ethel Browse this author | | Choongo, Kennedy Browse this author | | Kataba, Andrew Browse this author | | Chawinga, Kenneth Browse this author | | Liazambi, Allan Browse this author | | Nakayama, Shouta M. M. Browse this author →KAKEN DB | | Nakata, Hokuto Browse this author | | Ishizuka, Mayumi Browse this author →KAKEN DB |
| Keywords: | human health risk | | milk | | lead | | food safety | | ingestion |
| Issue Date: | 14-Apr-2022 |
| Publisher: | MDPI |
| Journal Title: | International journal of environmental research and public health |
| Volume: | 19 |
| Issue: | 8 |
| Start Page: | 4757 |
| Publisher DOI: | 10.3390/ijerph19084757 |
| Abstract: | Lead (Pb) contamination in the environment affects both humans and animals. Chronic exposure to Pb via dietary intake of animal products such as milk from contaminated areas poses a health risk to consumers; therefore, the present study investigated Pb contamination in cow milk and its health risk impact on humans through consumption of milk from cattle reared in the proximity of a Pb-Zn mine in Kabwe, Zambia. Fresh milk samples were collected from cows from Kang'omba (KN), Kafulamse (KF), Mpima (MP), Mukobeko (MK), and Munga (MN) farming areas. Pb determination was performed using Graphite Flame Absorption Atomic Spectrophotometry (GFAAS). Cow milk Pb levels showed different concentration patterns according to season, distance, and location of the farms from the Pb-Zn mine. The overall mean Pb levels were ranged 0.60-2.22 mu g/kg and 0.50-4.24 mu g/kg in the wet and dry seasons, respectively. The mean Pb concentration, chronic daily intake (CDIs), target hazard quotients (THQs), and incremental lifetime cancer risk (ILCR) results obtained were all within the permissible limits of 20 mu g/kg, 3 and 12.5 mu g/kg-BW/day, <1 and 10(-4) to10(-6), respectively. In conclusion, although Pb was detected in milk from cows reared in Kabwe, the health risk effects of Pb exposure associated with the consumption of milk in both adults and children were negligible. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/85602 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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