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Accuracy of Swan-Ganz catheterization-based assessment of right ventricular function : Validation study using high-fidelity micromanometry-derived values as reference

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Title: Accuracy of Swan-Ganz catheterization-based assessment of right ventricular function : Validation study using high-fidelity micromanometry-derived values as reference
Authors: Shima, Hideki Browse this author
Nakaya, Toshitaka Browse this author
Tsujino, Ichizo Browse this author →KAKEN DB
Nakamura, Junichi Browse this author
Sugimoto, Ayako Browse this author
Sato, Takahiro Browse this author
Watanabe, Taku Browse this author →KAKEN DB
Ohira, Hiroshi Browse this author →KAKEN DB
Suzuki, Masaru Browse this author →KAKEN DB
Kato, Masaru Browse this author
Yokota, Isao Browse this author →KAKEN DB
Konno, Satoshi Browse this author →KAKEN DB
Keywords: high-fidelity micromanometry
pulmonary hypertension
right ventricular function
Swan-Ganz catheterization
Issue Date: 18-Apr-2022
Publisher: John Wiley & Sons
Journal Title: Pulmonary circulation
Volume: 12
Issue: 2
Start Page: e12078
Publisher DOI: 10.1002/pul2.12078
Abstract: Right ventricular (RV) function critically affects the outcomes of patients with pulmonary hypertension (PH). Pressure wave analysis using Swan-Ganz catheterization (SG-cath) allows for the calculation of indices of RV function. However, the accuracy of these indices has not been validated. In the present study, we calculated indices of systolic and diastolic RV functions using SG-cath-derived pressure recordings in patients with suspected or confirmed PH. We analyzed and validated the accuracies of three RV indices having proven prognostic values, that is, end-systolic elastance (Ees)/arterial elastance (Ea), beta (stiffness constant), and end-diastolic elastance (Eed), using high-fidelity micromanometry-derived data as reference. We analyzed 73 participants who underwent SG-cath for the diagnosis or evaluation of PH. In this study, Ees/Ea was calculated via the single-beat pressure method using [1.65 x (mean pulmonary arterial pressure) - 7.79] as end-systolic pressure. SG-cath-derived Ees/Ea, beta, and Eed were 0.89 +/- 0.69 (mean +/- standard deviation), 0.027 +/- 0.002, and 0.16 +/- 0.02 mmHg/ml, respectively. The mean differences (limits of agreement) between SG-cath and micromanometry-derived data were 0.13 (0.99, -0.72), 0.002 (0.020, -0.013), and 0.04 (0.20, -0.12) for Ees/Ea, beta, and Eed, respectively. The intraclass correlation coefficients of the indices derived from the two catheterizations were 0.76, 0.71, and 0.57 for Ees/Ea, beta, and Eed, respectively. In patients with confirmed or suspected PH, SG-cath-derived RV indices, especially Ees/Ea and beta, exhibited a good correlation with micromanometry-derived reference values.
Type: article
URI: http://hdl.handle.net/2115/85620
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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