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Hokkaido University Collection of Scholarly and Academic Papers >
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A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA
| Title: | A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA |
| Authors: | Baba, Kentaro Browse this author | | Kusumoto, Tamon Browse this author →KAKEN DB | | Okada, Shogo Browse this author →KAKEN DB | | Ishikawa, Masayori Browse this author →KAKEN DB |
| Issue Date: | 28-Jun-2021 |
| Publisher: | American Institute of Physics (AIP) |
| Journal Title: | Journal of Applied Physics |
| Volume: | 129 |
| Issue: | 24 |
| Start Page: | 244702 |
| Publisher DOI: | 10.1063/5.0054665 |
| Abstract: | Monte Carlo track structure simulation is a powerful method for estimating damage induced by water radiolysis products for cell killing. To investigate the influence of multiple ionization for the formation of water radiolysis products under H-1(+), He-4(2+), and C-12(6+) ion beams, a Monte Carlo simulation based on Geant4-DNA was carried out. The G-value of H2O2 increased monotonically with increasing linear energy transfer up to 200 eV/nm. Above 200 eV/nm, the G-value of H2O2 began dropping, but only when the influence of multiple ionization was considered. This trend is in good agreement with the experimental results. Furthermore, we successfully reproduce the experimental results of G-values of HO2 center dot + O-2(center dot-). The role of the multiple ionization in the production of H2O2, HO2 center dot, O-2(center dot-), and O-2 is also discussed. |
| Rights: | This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in "Baba, K. Kusumoto, T. Okada, S. Ishikawa, M. A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA. Journal of Applied Physics. 2021 129(24) 244702" and may be found at https://doi.org/10.1063/5.0054665 |
| Type: | article |
| URI: | http://hdl.handle.net/2115/86158 |
| Appears in Collections: | 保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 石川 正純
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