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Caging and photo-triggered uncaging of singlet oxygen by excited state engineering of electron donor-acceptor-linked molecular sensors
| Title: | Caging and photo-triggered uncaging of singlet oxygen by excited state engineering of electron donor-acceptor-linked molecular sensors |
| Authors: | Sasikumar, Devika Browse this author | | Takano, Yuta Browse this author | | Zhao, Hanjun Browse this author | | Kohara, Reiko Browse this author | | Hamada, Morihiko Browse this author | | Kobori, Yasuhiro Browse this author | | Biju, Vasudevanpillai Browse this author |
| Issue Date: | 5-Jul-2022 |
| Publisher: | Nature Portfolio |
| Journal Title: | Scientific reports |
| Volume: | 12 |
| Issue: | 1 |
| Start Page: | 11371 |
| Publisher DOI: | 10.1038/s41598-022-15054-4 |
| Abstract: | Singlet oxygen (O-1(2)), one of the most sought-after species in oxidative chemical reactions and photodynamic cancer therapy, is activated and neutralized in the atmosphere and living cells. It is essential to see when and where O-1(2) is produced and delivered to understand and utilize it. There is an increasing demand for molecular sensor tools to capture, store, and supply O-1(2), controlled by light and engineered singlet and triplet states, indicating the O-1(2)-capturing-releasing state. Here, we demonstrate the outstanding potential of an aminocoumarin-methylanthracene-based electron donor-acceptor molecule (1). Spectroscopic measurements confirm the formation of an endoperoxide (1-O-2) which is not strongly fluorescent and remarkably different from previously reported O-1(2) sensor molecules. Moreover, the photoexcitation on the dye in 1-O-2 triggers fluorescence enhancement by the oxidative rearrangement and a competing O-1(2) release. The unique ability of 1 will pave the way for the spatially and temporally controlled utilization of O-1(2) in various areas such as chemical reactions and phototherapies. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/86462 |
| Appears in Collections: | 電子科学研究所 (Research Institute for Electronic Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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