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Factor associated with oral candidiasis caused by co-infection of Candida albicans and Candida glabrata : A retrospective study

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Title: Factor associated with oral candidiasis caused by co-infection of Candida albicans and Candida glabrata : A retrospective study
Authors: Hato, Hiroyuki Browse this author
Sakata, Ken-ichiro Browse this author →KAKEN DB
Sato, Jun Browse this author →KAKEN DB
Hasebe, Akira Browse this author →KAKEN DB
Yamazaki, Yutaka Browse this author →KAKEN DB
Kitagawa, Yoshimasa Browse this author →KAKEN DB
Keywords: Oral candidiasis
Candida albicans
Candida glabrata
Co-infection
Issue Date: Jul-2022
Publisher: Elsevier
Journal Title: Journal of dental sciences
Volume: 17
Issue: 3
Start Page: 1458
End Page: 1461
Publisher DOI: 10.1016/j.jds.2021.10.020
PMID: 35784140
Abstract: This study aimed to determine the factors associated with the co-infection of Candida albicans and Candida glabrata. This retrospective study conducted between January 2015 and 2020 comprised 131 patients who were diagnosed with oral candidiasis. The factors associated with this condition were analyzed by univariate and multivariate logistic regression. Age and denture use were identified as significant risk factors in the univariate analysis. The multivariate logistic regression analysis revealed that denture use (odds ratio [OR], 8.44 95% confidence interval [CI], 1.99-28.3) and immunosuppressive therapy (OR, 9.20; 95% CI, 1.19 -62.0) had significant effects on co-infection with the two Candida species. These findings suggest that immunosuppressive therapy using and dentures is significantly associated with oral candidiasis caused by co-infection of C. albicans and C. glabrata. (C) 2021 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.
Type: article
URI: http://hdl.handle.net/2115/86764
Appears in Collections:歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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