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Hokkaido University Collection of Scholarly and Academic Papers >
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Malignant oligoastrocytoma in the spinal cord of a cat
| Title: | Malignant oligoastrocytoma in the spinal cord of a cat |
| Authors: | Hasegawa, Dai Browse this author | | Aoshima, Keisuke Browse this author | | Sasaoka, Kazuyoshi Browse this author | | Kobayashi, Atsushi Browse this author | | Takiguchi, Mitsuyoshi Browse this author →KAKEN DB | | Kimura, Takashi Browse this author →KAKEN DB |
| Keywords: | cat | | Ki-67 | | oligoastrocytoma | | spinal cord | | tumor |
| Issue Date: | 12-Sep-2022 |
| Publisher: | 公益社団法人 日本獣医学会 (The Japanese Society of Veterinary Science) |
| Journal Title: | Journal of veterinary medical science |
| Volume: | 84 |
| Issue: | 9 |
| Start Page: | 1277 |
| End Page: | 1282 |
| Publisher DOI: | 10.1292/jvms.22-0144 |
| Abstract: | A 12-year and 3-month spayed female mixed cat was presented with severe lumbar pain. Magnetic resonance imaging and postmortem examination revealed a swollen lesion in the spinal cord at L3 level. Histologic examination identified extensive neoplastic cell proliferation with massive necrosis in the tumor tissue. Two types of neoplastic cells were recognized. One type of neoplastic cells were large cells characterized by round to polygonal shape and abundant eosinophilic cytoplasm (referred to as large cells). The other neoplastic cells were small, densely proliferated, and had round to irregular shape and scant eosinophilic cytoplasm (referred to as small cells). Both types of cells were positive for oligodendrocyte transcription factor 2 and SRY-box transcription factor 10. Glial fibrillary acidic protein was positive in large cells but negative in most small cells. Digital analysis for Ki-67-stained tumor tissues found that total 21.1% +/- 6.5% of tumor cells were positive for Ki-67. Based on these findings, we diagnosed malignant oligoastrocytoma in the spinal cord. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/87311 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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