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Association between indoor exposure to semi-volatile organic compounds and building-related symptoms among the occupants of residential dwellings
| Title: | Association between indoor exposure to semi-volatile organic compounds and building-related symptoms among the occupants of residential dwellings |
| Authors: | Kanazawa, A. Browse this author | | Saito, I. Browse this author | | Araki, A. Browse this author →KAKEN DB | | Takeda, M. Browse this author | | Ma, M. Browse this author | | Saijo, Y. Browse this author | | Kishi, R. Browse this author →KAKEN DB |
| Issue Date: | Feb-2010 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Indoor Air |
| Volume: | 20 |
| Issue: | 1 |
| Start Page: | 72 |
| End Page: | 84 |
| Publisher DOI: | 10.1111/j.1600-0668.2009.00629.x |
| Abstract: | The aim of this study was to evaluate the levels of semi-volatile compounds (SVOCs) in residential detached houses in Sapporo, Japan, and whether exposure to these SVOCs was associated with the development of building-related symptoms named ‘sick house syndrome’ (SHS). The definition of SHS is fundamentally the same as that of the sick building syndrome (SBS). The presence of symptoms of SHS was evaluated using a validated self-administered questionnaire. Surveys and samplings of air and house dust in 41 dwellings were performed from October 2006 to January 2007, and 134 occupants responded to questionnaires. Samples were analyzed to quantify the concentrations of eight plasticizers, eleven phosphate triester flame retardants, two alkyl phenols used as anti-oxidants, and one organochlorine synergist called s-421, by gas chromatography–mass spectrometry and gas chromatography–flame photometry. The compounds frequently detected were di-n-butylphthalate, di(2-ethylhexyl)phthalate (DEHP), and dibutylhydroxytoluene in air, and DEHP and tris(2-butoxyethyl)phosphate (TBEP) in dust. Tributylphosphate was strongly and directly associated with mucosal symptoms of SHS; s-421 was also directly associated with mucosal symptoms of SHS. On the contrary, some chemicals such as diethylphthalate and TBEP were inversely associated with SHS. In future studies, we plan to assess these associations in a larger population. |
| Rights: | This is the pre-peer-reviewed version of the following article: Kanazawa, A., Saito, I., Araki, A., Takeda, M., Ma, M., Saijo, Y. and Kishi, R. (2010), Association between indoor exposure to semi-volatile organic compounds and building-related symptoms among the occupants of residential dwellings. Indoor Air, 20: 72-84, which has been published in final form at https://doi.org/10.1111/j.1600-0668.2009.00629.x |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/87324 |
| Appears in Collections: | 環境健康科学研究教育センター (Center for Environmental and Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 岸 玲子
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