| Title: | Molecular identification and risk factor analysis of the first Lumpy skin disease outbreak in cattle in Mongolia |
| Authors: | Odonchimeg, Myagmarsuren Browse this author |
| Erdenechimeg, Dashzevge Browse this author |
| Tuvshinbayar, Adiyasuren Browse this author |
| Tsogtgerel, Munkhtuul Browse this author |
| Bazarragchaa, Enkhbold Browse this author |
| Ulaankhuu, Ankhanbaatar Browse this author |
| Selenge, Tsend Browse this author |
| Munkhgerel, Dalantai Browse this author |
| Munkhtsetseg, Ariunbold Browse this author |
| Altanchimeg, Adilbish Browse this author |
| Odbileg, Raadan Browse this author |
| Soyolmaa, Gurdorj Browse this author |
| Enkhmandakh, Yondonjamts Browse this author |
| Batmagnai, Enkhbaatar Browse this author |
| Sugar, Sengee Browse this author |
| Kimura, Takashi Browse this author →KAKEN DB |
| Sugimoto, Chihiro Browse this author |
| Isoda, Norikazu Browse this author →KAKEN DB |
| Batsukh, Basan Browse this author |
| Sakoda, Yoshihiro Browse this author →KAKEN DB |
| Keywords: | lumpy skin disease |
| molecular identification |
| Mongolia |
| outbreak |
| risk factor |
| Issue Date: | 5-Sep-2022 |
| Publisher: | 公益社団法人 日本獣医学会 (The Japanese Society of Veterinary Science) |
| Journal Title: | Journal of veterinary medical science |
| Volume: | 84 |
| Issue: | 9 |
| Start Page: | 1244 |
| End Page: | 1252 |
| Publisher DOI: | 10.1292/jvms.22-0250 |
| Abstract: | Lumpy skin disease (LSD) is a transboundary viral infectious disease in cattle caused by a Capripoxvirus. LSD has been recently introduced in some Asian countries. However, in Mongolia, no report of LSD is publicly available. We clinically examined LSD symptoms in 1,034 cattle from 4 soum (district) in Dornod province in Mongolia. Sixty-one cattle of them were confirmed with symptoms of LSD and then viral P32 gene was detected by a PCR. The overall prevalence of LSD in cattle was 5.9%. Females odds ratios (OR)=2.27 than males, adults (>2.5-years-old, OR=3.68) than young (1-2.5-years-old) and calves (<1-year-old) were at higher risks for LSD cases in Mongolia, while locations near the tube well and pond water are major risk areas for viral transmission due to density of insects often is high. For virus isolation, skin nodule tissue samples of 4 cattle located in four distinct soums were used for viral propagation using the MDBK cell line. Internal terminal repeat region and RPO30 gene of 4 Mongolian isolates were amplified and sequenced. In the phylogenetic trees, Mongolian LSDVs (2021) were clustered together with the Chinese (2020) and Vietnamese isolates (2020). This is the first report alarming the LSD outbreak in Mongolia that was confirmed by our study. The newly isolated viruses would be a useful base for developing diagnostic tools and inactivated vaccine technology. A large-scale study of LSD is next priority for establishing successful control strategy of further disease outbreak. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/87330 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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