HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Peer-reviewed Journal Articles, etc >

Molecular identification and risk factor analysis of the first Lumpy skin disease outbreak in cattle in Mongolia

Files in This Item:

The file(s) associated with this item can be obtained from the following URL:

Title: Molecular identification and risk factor analysis of the first Lumpy skin disease outbreak in cattle in Mongolia
Authors: Odonchimeg, Myagmarsuren Browse this author
Erdenechimeg, Dashzevge Browse this author
Tuvshinbayar, Adiyasuren Browse this author
Tsogtgerel, Munkhtuul Browse this author
Bazarragchaa, Enkhbold Browse this author
Ulaankhuu, Ankhanbaatar Browse this author
Selenge, Tsend Browse this author
Munkhgerel, Dalantai Browse this author
Munkhtsetseg, Ariunbold Browse this author
Altanchimeg, Adilbish Browse this author
Odbileg, Raadan Browse this author
Soyolmaa, Gurdorj Browse this author
Enkhmandakh, Yondonjamts Browse this author
Batmagnai, Enkhbaatar Browse this author
Sugar, Sengee Browse this author
Kimura, Takashi Browse this author →KAKEN DB
Sugimoto, Chihiro Browse this author
Isoda, Norikazu Browse this author →KAKEN DB
Batsukh, Basan Browse this author
Sakoda, Yoshihiro Browse this author →KAKEN DB
Keywords: lumpy skin disease
molecular identification
risk factor
Issue Date: 5-Sep-2022
Publisher: 公益社団法人 日本獣医学会 (The Japanese Society of Veterinary Science)
Journal Title: Journal of veterinary medical science
Volume: 84
Issue: 9
Start Page: 1244
End Page: 1252
Publisher DOI: 10.1292/jvms.22-0250
Abstract: Lumpy skin disease (LSD) is a transboundary viral infectious disease in cattle caused by a Capripoxvirus. LSD has been recently introduced in some Asian countries. However, in Mongolia, no report of LSD is publicly available. We clinically examined LSD symptoms in 1,034 cattle from 4 soum (district) in Dornod province in Mongolia. Sixty-one cattle of them were confirmed with symptoms of LSD and then viral P32 gene was detected by a PCR. The overall prevalence of LSD in cattle was 5.9%. Females odds ratios (OR)=2.27 than males, adults (>2.5-years-old, OR=3.68) than young (1-2.5-years-old) and calves (<1-year-old) were at higher risks for LSD cases in Mongolia, while locations near the tube well and pond water are major risk areas for viral transmission due to density of insects often is high. For virus isolation, skin nodule tissue samples of 4 cattle located in four distinct soums were used for viral propagation using the MDBK cell line. Internal terminal repeat region and RPO30 gene of 4 Mongolian isolates were amplified and sequenced. In the phylogenetic trees, Mongolian LSDVs (2021) were clustered together with the Chinese (2020) and Vietnamese isolates (2020). This is the first report alarming the LSD outbreak in Mongolia that was confirmed by our study. The newly isolated viruses would be a useful base for developing diagnostic tools and inactivated vaccine technology. A large-scale study of LSD is next priority for establishing successful control strategy of further disease outbreak.
Type: article
Appears in Collections:獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Export metadata:

OAI-PMH ( junii2 , jpcoar_1.0 )

MathJax is now OFF:


 - Hokkaido University