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Predictors of cardiovascular mortality after an electrical storm in patients with structural heart disease

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Title: Predictors of cardiovascular mortality after an electrical storm in patients with structural heart disease
Authors: Koizumi, Takuya Browse this author
Kamada, Rui Browse this author →KAKEN DB
Watanabe, Masaya Browse this author →KAKEN DB
Yokoshiki, Hisashi Browse this author
Temma, Taro Browse this author
Hagiwara, Hikaru Browse this author
Koya, Taro Browse this author
Nakao, Motoki Browse this author
Kadosaka, Takahide Browse this author
Natsui, Hiroyuki Browse this author
Takahashi, Masayuki Browse this author
Mizukami, Kazuya Browse this author
Mitsuyama, Hirofumi Browse this author
Anzai, Toshihisa Browse this author →KAKEN DB
Keywords: Electrical storm
Defibrillator shock
Cardiovascular mortality
Heart failure
Issue Date: Aug-2022
Publisher: Elsevier
Journal Title: Journal of cardiology
Volume: 80
Issue: 2
Start Page: 167
End Page: 171
Publisher DOI: 10.1016/j.jjcc.2022.02.016
Abstract: Background: Electrical storms (ESs) in patients with structural heart disease (SHD) have been reported to be associated with a poor prognosis. However, the detailed cause of death and influence of implantable cardioverter defibrillator (ICD) therapy in ES patients have not been fully investigated. Therefore, we sought to explore the detailed clinical course after an ES and the impact of the ICD therapy in patients with SHDs. Methods: We retrospectively analyzed 31 consecutive patients with ESs who had undergone a n1CD implantation. ESs were defined as three or more ventricular arrhythmias within 24 h. Results: During a mean follow up of 4.5 years, 13 patients died. Among them, cardiovascular death (CVD) was observed in 11/13 (85%), and the leading cause of the CVD was end-stage heart failure. A New York Heart Association class >= III at the time of the ES occurrence (HR 6.51 95% CI 1.94-25.1, p = 0.003) and any shock therapy (HR 5.94 95% CI 1.06-112.2, p = 0.04) were associated with CVD. Conclusion: In the current single center study, the major cause of death in ES patients with SHDs was end-stage heart failure. Any shock therapy was associated with CVD. Arrhythmia management to avoid ICD shocks might reduce the mortality in ES patients. (C) 2022 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. All rights reserved.
Type: article
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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