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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Effects of the Interaction between Affective Temperaments and BIS/BAS on Depressive Symptoms in Individuals with Major Depressive Disorder
| Title: | Effects of the Interaction between Affective Temperaments and BIS/BAS on Depressive Symptoms in Individuals with Major Depressive Disorder |
| Authors: | Toyoshima, Kuniyoshi Browse this author →KAKEN DB | | Masuya, Jiro Browse this author | | Ono, Miki Browse this author | | Honyashiki, Mina Browse this author | | Hashimoto, Shogo Browse this author | | Kusumi, Ichiro Browse this author →KAKEN DB | | Inoue, Takeshi Browse this author |
| Keywords: | affective temperaments | | behavioral activation system | | behavioral inhibition system | | depression | | interaction | | major depressive disorder |
| Issue Date: | Dec-2022 |
| Publisher: | MDPI |
| Journal Title: | International journal of environmental research and public health |
| Volume: | 19 |
| Issue: | 23 |
| Start Page: | 15841 |
| Publisher DOI: | 10.3390/ijerph192315841 |
| Abstract: | Depressive symptoms (DepS) associated with major depressive disorder (MDD) are influenced by affective temperaments (ATs), behavioral inhibition system (BIS), and behavioral activation system (BAS). However, the effect of interactions between ATs and BIS/BAS on DepS in MDD remains poorly understood. Herein, we aimed to investigate the effects of these interactions. The Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Auto-questionnaire (TEMPS-A), BIS/BAS questionnaire, and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate ATs, BIS/BAS, and DepS, respectively, in 90 participants with MDD. Data were analyzed using hierarchical multiple regression analysis to assess the interaction effect. The interaction (beta = 0.199, p < 0.05) between depressive temperament (DepT) (beta = 0.319, p < 0.01) and BIS scores (beta = 0.300, p < 0.01) exhibited a significant positive effect on DepS (Delta R-2 = 0.038, p < 0.05). However, the interaction between ATs and BAS scores did not exhibit a significant effect on DepS. Our findings suggest that interactions between BIS sensitivity and DepT worsen DepS in individuals with MDD. Hence, to manage DepS associated with BIS sensitivity and DepT, evaluating their interaction may be useful in daily clinical practice. This study presents important insights into MDD psychopathology. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/88082 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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