| Title: | Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa) |
| Authors: | Baba, Haruhisa Browse this author |
| Watanabe, Yutaka Browse this author →KAKEN DB |
| Miura, Kazuhito Browse this author |
| Ozaki, Kimiya Browse this author →KAKEN DB |
| Matsushita, Takae Browse this author |
| Kondoh, Miyako Browse this author →KAKEN DB |
| Okada, Kazutaka Browse this author →KAKEN DB |
| Hasebe, Akira Browse this author →KAKEN DB |
| Ayabe, Tokiyoshi Browse this author →KAKEN DB |
| Nakamura, Kiminori Browse this author →KAKEN DB |
| Nakaoka, Shinji Browse this author →KAKEN DB |
| Ogasawara, Katsuhiko Browse this author →KAKEN DB |
| Suzuki, Teppei Browse this author |
| Saito, Hiroshi Browse this author →KAKEN DB |
| Kimura, Takashi Browse this author →KAKEN DB |
| Tamakoshi, Akiko Browse this author →KAKEN DB |
| Yamazaki, Yutaka Browse this author →KAKEN DB |
| Keywords: | Candida albicans |
| Candida glabrata |
| community-dwelling older adults |
| cross-sectional study |
| internal transcribed spacer 2 |
| oral frailty |
| Issue Date: | 31-Jan-2022 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Gerodontology |
| Volume: | 39 |
| Issue: | 1 |
| Start Page: | 49 |
| End Page: | 58 |
| Publisher DOI: | 10.1111/ger.12621 |
| PMID: | 35098575 |
| Abstract: | Objective To examine the association between oral frailty and oral Candida carriage as a general indicator of deteriorating oral function in older adults. Background Older adults exhibit an elevated risk of oral candidiasis caused by Candida. Although many studies have identified factors associated with oral Candida carriage, none have evaluated its relationship with oral function. Materials and Methods This study included 210 community-dwelling older adults aged >= 60 years who participated in wellness checks. Fungal flora expression in saliva samples was evaluated to identify oral C. albicans and C. glabrata. Participants were categorised by detection of neither strain (group 1), either one of the strains (group 2), or both strains (group 3). The relationship between oral Candida carriage and oral frailty was evaluated by multinomial logistic regression analysis. Results The participants included 58 men and 152 women with a mean age of 74.2 +/- 6.1 years. A total of 88 (41.9%), 94 (44.8%) and 28 (13.3%) participants were assigned to groups 1, 2 and 3 respectively. In the multinomial logistic regression analysis, significant associations were observed between group 1 and group 2 for "Have you choked on your tea or soup recently?" and the number of applicable oral frailty items. Between group 1 and group 3, significant associations were observed for the number of remaining teeth, masticatory performance and the number of applicable oral frailty items. Conclusion We obtained basic data useful for intervention studies aimed at verifying whether oral function management prevents deterioration of the oral bacterial flora. |
| Rights: | This is the peer reviewed version of the following article: Baba H, Watanabe Y, Miura K, Ozaki K, Matsushita T, Kondoh M, Okada K, Hasebe A, Ayabe T, Nakamura K, Nakaoka S, Ogasawara K, Suzuki T, Saito H, Kimura T, Tamakoshi A, Yamazaki Y. Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa). Gerodontology. 2022 Mar;39(1):49-58., which has been published in final form at https://doi.org/10.1111/ger.12621. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/88200 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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