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Age Estimation from Brain Magnetic Resonance Images Using Deep Learning Techniques in Extensive Age Range

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Title: Age Estimation from Brain Magnetic Resonance Images Using Deep Learning Techniques in Extensive Age Range
Authors: Usui, Kousuke Browse this author
Yoshimura, Takaaki Browse this author →KAKEN DB
Tang, Minghui Browse this author →KAKEN DB
Sugimori, Hiroyuki Browse this author →KAKEN DB
Keywords: deep learning
age estimation
regression model
machine learning
ResNet-50
Issue Date: 30-Jan-2023
Publisher: MDPI
Journal Title: Applied sciences
Volume: 13
Issue: 3
Start Page: 1753
Publisher DOI: 10.3390/app13031753
Abstract: Estimation of human age is important in the fields of forensic medicine and the detection of neurodegenerative diseases of the brain. Particularly, the age estimation methods using brain magnetic resonance (MR) images are greatly significant because these methods not only are noninvasive but also do not lead to radiation exposure. Although several age estimation methods using brain MR images have already been investigated using deep learning, there are no reports involving younger subjects such as children. This study investigated the age estimation method using T1-weighted (sagittal plane) two-dimensional brain MR imaging (MRI) of 1000 subjects aged 5-79 (31.64 +/- 18.04) years. This method uses a regression model based on ResNet-50, which estimates the chronological age (CA) of unknown brain MR images by training brain MR images corresponding to the CA. The correlation coefficient, coefficient of determination, mean absolute error, and root mean squared error were used as the evaluation indices of this model, and the results were 0.9643, 0.9299, 5.251, and 6.422, respectively. The present study showed the same degree of correlation as those of related studies, demonstrating that age estimation can be performed for a wide range of ages with higher estimation accuracy.
Type: article
URI: http://hdl.handle.net/2115/88583
Appears in Collections:保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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