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Prevention of Root Caries Using Oxalic Acid
| Title: | Prevention of Root Caries Using Oxalic Acid |
| Authors: | Oguma, Hidetoshi Browse this author | | Matsuda, Yasuhiro Browse this author →KAKEN DB | | Yoshihara, Kumiko Browse this author →KAKEN DB | | Okuyama, Katsushi Browse this author →KAKEN DB | | Sakurai, Masahiko Browse this author | | Saito, Takashi Browse this author →KAKEN DB | | Inoue, Satoshi Browse this author →KAKEN DB | | Yoshida, Yasuhiro Browse this author →KAKEN DB |
| Keywords: | oxalic acid | | polyacrylic acid | | root caries | | hypersensitivity | | automatic pH cycle |
| Issue Date: | 9-Feb-2023 |
| Publisher: | MDPI |
| Journal Title: | Materials |
| Volume: | 16 |
| Issue: | 4 |
| Start Page: | 1454 |
| Publisher DOI: | 10.3390/ma16041454 |
| PMID: | 36837083 |
| Abstract: | Certain dentin hypersensitivity treatment materials include oxalic acid to coat dentin surfaces with minerals, while certain organic acids possess a remineralization effect. Herein, an organic acid that inhibits the demineralization and coating of root surfaces was evaluated. Specimens were produced using five non-carious extracted bovines. Four different acids were used: oxalic acid (OA), malonic acid (MA), polyacrylic acid (PA), and succinic acid (SA). Each acid was applied to the root surface and washed using distilled water or a remineralization solution, and the surface was observed using scanning electron microscopy (SEM). All the surfaces of each specimen, barring the polished surface, were covered with wax and immersed in an automatic pH cycling system for two weeks. Dentin demineralization was analyzed using transverse microradiography (TMR) before and after pH cycling. SEM analysis demonstrated that the three acid groups demineralized the dentin surface, whereas the OA group generated crystals covering the dentin surface, even in a distilled water environment. TMR analysis revealed that the OA groups showed significantly lower integrated mineral loss compared with the other groups, even in the distilled water environment. The results suggest that OA generates insoluble calcium oxalate crystals on the dentin and suppresses demineralization even under low saliva conditions. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/89031 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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