| Title: | Changes in circulating insulin-like growth factor-1 and its binding proteins in yearling rainbow trout during spring under natural and manipulated photoperiods and their relationships with gill Na+, K+-ATPase and body size |
| Authors: | Cui, Wenda Browse this author |
| Takahashi, Eisuke Browse this author |
| Morro, Bernat Browse this author |
| Balseiro, Pablo Browse this author |
| Albalat, Amaya Browse this author |
| Pedrosa, Cindy Browse this author |
| Mackenzie, Simon Browse this author |
| Nilsen, Tom O. Browse this author |
| Sveier, Harald Browse this author |
| Ebbesson, Lars O. Browse this author |
| Handeland, Sigurd O. Browse this author |
| Shimizu, Munetaka Browse this author →KAKEN DB |
| Keywords: | Body size |
| Feeding restriction |
| Hypo-osmoregulatory ability |
| IGFBP-2b |
| Smoltification |
| Issue Date: | Jun-2022 |
| Publisher: | Elsevier |
| Journal Title: | Comparative Biochemistry and Physiology Part A : molecular & integrative physiology |
| Volume: | 268 |
| Start Page: | 111205 |
| Publisher DOI: | 10.1016/j.cbpa.2022.111205 |
| Abstract: | Smoltification in salmonids occurs during spring in response to increasing photoperiod to prepare for marine life. Smoltification is associated with increased hypo-osmoregulatory ability and enhanced growth potential, mediated by growth hormone and insulin-like growth factor (IGF)-1. Rainbow trout is uniquely insensitive to the induction of smoltification-associated changes by photoperiod, such as the activation of gill Na+,K+-ATPase (NKA). We measured the circulating IGF-1 and IGF-binding protein (IGFBP)-2b levels in yearling rainbow trout exposed to natural and manipulated photoperiods during spring and correlated these with gill NKA activity and body size. Although the effect of photoperiod manipulation on body size and circulating IGF-1 and IGFBP-2b was negligible, they were positively correlated with gill NKA activity in fish under simulated natural photoperiod. We next pit-tagged yearling rainbow trout and fed them a restricted ration or to satiation under a natural photo period. In April, gill NKA activity was higher in the satiation group than in the restricted group and positively correlated with body size and growth rate. In addition, circulating IGFBP-2b was positively correlated with gill NKA, size and growth, whereas circulating IGF-1 was correlated only with size and growth. The relationship between circulating IGF-1 and growth intensified from May to June, suggesting that the IGF-1-growth relationship was disrupted in April when gill NKA was activated. Two additional IGFBPs were related to growth parameters but not to gill NKA activity. The present study suggests that circulating IGFBP-2b and IGF-1 mediate the size-dependent activation of gill NKA in yearling rainbow trout during spring. |
| Rights: | © <2022>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/89370 |
| Appears in Collections: | 水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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