| Title: | Outcomes of laparoscopic total gastrectomy in elderly patients : a propensity score matching analysis |
| Authors: | Ebihara, Yuma Browse this author →KAKEN DB |
| Kurashima, Yo Browse this author →KAKEN DB |
| Watanabe, Yusuke Browse this author |
| Tanaka, Kimitaka Browse this author →KAKEN DB |
| Matsui, Aya Browse this author →KAKEN DB |
| Nakanishi, Yoshitsugu Browse this author |
| Asano, Toshimichi Browse this author |
| Noji, Takehiro Browse this author →KAKEN DB |
| Nakamura, Toru Browse this author |
| Murakami, Soichi Browse this author |
| Tsuchikawa, Takahiro Browse this author →KAKEN DB |
| Okamura, Keisuke Browse this author |
| Murakami, Yoshihiro Browse this author |
| Murakawa, Katsuhiko Browse this author |
| Nakamura, Fumitaka Browse this author |
| Morita, Takayuki Browse this author |
| Okushiba, Shunichi Browse this author |
| Shichinohe, Toshiaki Browse this author →KAKEN DB |
| Hirano, Satoshi Browse this author →KAKEN DB |
| Keywords: | Laparoscopic total gastrectomy |
| Gastric cancer |
| Elderly patients |
| Multicenter retrospective study |
| Issue Date: | 1-Jun-2022 |
| Publisher: | Springer |
| Journal Title: | Langenbeck's archives of surgery |
| Volume: | 407 |
| Issue: | 4 |
| Start Page: | 1461 |
| End Page: | 1469 |
| Publisher DOI: | 10.1007/s00423-022-02447-2 |
| Abstract: | Purpose This study evaluated the short-term outcomes and prognosis after laparoscopic total gastrectomy (LTG) in elderly patients aged >= 80 years in a multicenter retrospective cohort study using propensity score matching. Methods We retrospectively enrolled 440 patients who underwent curative LTG for gastric cancer at six institutions between January 2004 and December 2018. Patients were categorized into an elderly patient group (EG; age >= 80 years) and non-elderly patient group (non-EG; age < 80 years). Patients were matched using the following propensity score covariates: sex, body mass index, American Society of Anesthesiologists physical status, extent of lymph node dissection, and Japanese Classification of Gastric Carcinoma stage. Short-term outcomes and prognoses were compared. Results We identified 37 propensity score-matched pairs. The median operative time was significantly shorter, and postoperative stay was longer in the EG. In terms of postoperative outcomes, the rates of all complications were comparable. The median follow-up period of the EG and non-EG was 11.5 (1-106.4) months and 35.7 (1-110.0) months, respectively; there were significant differences in 5-year overall survival between the two groups (EG, 58.5% vs. non-EG, 91.5%; P = 0.031). However, there were no significant differences in 5-year disease-specific survival (EG, 62.1% vs. non-EG, 91.5%; P = 0.068) or 5-year disease-free survival (EG, 52.9% vs. non-EG, 60.8%; P = 0.132). Conclusions LTG seems to be safe and feasible in elderly patients. LTG had a limited effect on morbidity, disease recurrence, and survival in elderly patients. Therefore, age should not prevent elderly patients from benefitting from LTG. |
| Rights: | This is a post-peer-review, pre-copyedit version of an article published in Langenbeck's archives of surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00423-022-02447-2 |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/89786 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
