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Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa)

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Please use this identifier to cite or link to this item:https://doi.org/10.14943/doctoral.k15493
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Title: Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa)
Other Titles: 地域在住高齢者におけるオーラルフレイルと口腔カンジダの保菌状態との関連
Authors: 馬場, 陽久 Browse this author
Keywords: Candida albicans
Candida glabrata
community-dwelling older adults
cross-sectional study
internal transcribed spacer 2
oral frailty
Issue Date: 23-Mar-2023
Publisher: Hokkaido University
Abstract: Objective: To examine the association between oral frailty and oral Candida carriage as a general indicator of deteriorating oral function in older adults. Background: Older adults exhibit an elevated risk of oral candidiasis caused by Candida. Although many studies have identified factors associated with oral Candida carriage, none have evaluated its relationship with oral function. Materials and Methods: This study included 210 community-dwelling older adults aged ≥60 years who participated in wellness checks. Fungal flora expression in saliva samples was evaluated to identify oral C. albicans and C. glabrata. Participants were categorised by detection of neither strain (group 1), either one of the strains (group 2), or both strains (group 3). The relationship between oral Candida carriage and oral frailty was evaluated by multinomial logistic regression analysis. Results: The participants included 58 men and 152 women with a mean age of 74.2 ± 6.1 years. A total of 88 (41.9%), 94 (44.8%) and 28 (13.3%) participants were assigned to groups 1, 2 and 3 respectively. In the multinomial logistic regression analysis, significant associations were observed between group 1 and group 2 for “Have you choked on your tea or soup recently?” and the number of applicable oral frailty items. Between group 1 and group 3, significant associations were observed for the number of remaining teeth, masticatory performance and the number of applicable oral frailty items.Conclusion: We obtained basic data useful for intervention studies aimed at verifying whether oral function management prevents deterioration of the oral bacterial flora.
Conffering University: 北海道大学
Degree Report Number: 甲第15493号
Degree Level: 博士
Degree Discipline: 歯学
Examination Committee Members: (主査) 教授 山崎 裕, 教授 北川 善政, 教授 長谷部 晃, 准教授 渡邊 裕
Degree Affiliation: 歯学院(口腔医学専攻)
(Relation)isversionof: Baba H, Watanabe Y, Miura K, Ozaki K, Matsushita T, Kondoh M, Okada K, Hasebe A, Ayabe T, Nakamura K, Nakaoka S, Ogasawara K, Suzuki T, Saito H, Kimura T, Tamakoshi A, Yamazaki Y. Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa). Gerodontology. 2022 Mar;39(1):49-58.
https://doi.org/10.1111/ger.12621
Type: theses (doctoral)
URI: http://hdl.handle.net/2115/89889
Appears in Collections:課程博士 (Doctorate by way of Advanced Course) > 歯学院(Graduate School of Dental Medicine)
学位論文 (Theses) > 博士 (歯学)

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