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Synchronous colon cancer after treatment for rectal follicular lymphoma : A case report

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Title: Synchronous colon cancer after treatment for rectal follicular lymphoma : A case report
Authors: Saito, Makoto Browse this author
Egami, Hiroki Browse this author
Kato, Takashi Browse this author
Yokoyama, Emi Browse this author
Izumiyama, Koh Browse this author
Mori, Akio Browse this author
Morioka, Masanobu Browse this author
Kondo, Takeshi Browse this author
Tanei, Zen-Ichi Browse this author →KAKEN DB
Keywords: synchronous cancer
follicular lymphoma
colorectal lymphoma
sigmoid colon cancer
Issue Date: Aug-2022
Publisher: Spandidos Publications
Journal Title: Molecular and clinical oncology
Volume: 17
Issue: 2
Start Page: 129
Publisher DOI: 10.3892/mco.2022.2562
Abstract: Colorectal follicular lymphoma (FL) is rare. In addition, it is even rarer that colon cancer develops synchronously with colorectal lymphoma. The present study reports a case of sigmoid colon cancer that developed 6 months after endoscopic resection of rectal FL. A 71-year-old man with a history of developing mucosa-associated lymphoid tissue lymphoma in his stomach at age 48, right neck region at age 59 (the latter later modified as FL) and lung adenocarcinoma at age 60 now suffers from rectal FL. Endoscopic submucosal dissection (ESD) was performed at our hospital (Aiiku Hospital), and 6 months after the treatment, sigmoid colon cancer was confirmed by colonoscopy for the follow-up study. The patient was successfully curatively resected by ESD plus local resection and has survived without a recurrence for >3 years with no treatment. It was speculated that in the present case, cancer-related genes were changed as a carcinogenic mechanism due to decreased immune function associated with the onset of lymphoma.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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