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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Environmental Science / Faculty of Environmental Earth Science >
Peer-reviewed Journal Articles, etc >
Syntheses and Biological Activities of Danicalipin A Derivatives
| Title: | Syntheses and Biological Activities of Danicalipin A Derivatives |
| Authors: | Umezawa, Taiki Browse this author →KAKEN DB | | Maeda, Takeshi Browse this author | | Akiyama, Takuya Browse this author | | Prakoso, Nurcahyo Iman Browse this author | | Mehjabin, Jakia Jerin Browse this author | | Okino, Tatsufumi Browse this author →KAKEN DB | | Matsuda, Fuyuhiko Browse this author →KAKEN DB |
| Keywords: | chlorosulfolipids | | fluorescent probe | | structure-activity relationship |
| Issue Date: | Jun-2023 |
| Publisher: | Wiley-Blackwell |
| Journal Title: | Chemistry and Biodiversity |
| Volume: | 20 |
| Issue: | 6 |
| Start Page: | e202300400 |
| Publisher DOI: | 10.1002/cbdv.202300400 |
| Abstract: | Synthesis of three derivatives of danicalipin A, tetrachloride, trisulfate and a fluorescent probe was achieved through Wittig reaction strategy. Toxicity of the derivatives against brine shrimp (Artemia salina) as also investigated to provide useful information for the biological activity; i) less chloride derivative showed similar toxicity to danicalipin A, ii) the amphiphilic property, a characteristic feature of danicalipin A, was crucial because trisulfate considerably decreased the toxicity and iii) fluorescent derivative kept brine shrimp toxicity of danicalipin A. |
| Rights: | This is the peer reviewed version of the following article: Taiki Umezawa, Takeshi Maeda, Takuya Akiyama, Nurcahyo Iman Prakoso, Jakia Jerin Mehjabin, Tatsufumi Okino, Fuyuhiko Matsuda. Syntheses and Biological Activities of Danicalipin A Derivatives. Chemistry & Biodiversity: Volume 20, Issue 6. e202300400. June 2023, which has been published in final form at https://doi.org/10.1002/cbdv.202300400. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/92675 |
| Appears in Collections: | 環境科学院・地球環境科学研究院 (Graduate School of Environmental Science / Faculty of Environmental Earth Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 梅澤 大樹
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