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Hokkaido University Collection of Scholarly and Academic Papers >
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博士 （医学） >
Mechanisms of NLRC5 nuclear import and retention for enhanced MHC class I transactivation
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| Title: | Mechanisms of NLRC5 nuclear import and retention for enhanced MHC class I transactivation |
| Other Titles: | NLRC5の核内輸送および保持によるMHCクラスI転写活性の増強メカニズム |
| Authors: | 朱, 宝慧 Browse this author |
| Issue Date: | 28-Jun-2024 |
| Publisher: | Hokkaido University |
| Conffering University: | 北海道大学 |
| Degree Report Number: | 甲第16056号 |
| Degree Level: | 博士 |
| Degree Discipline: | 医学 |
| Examination Committee Members: | (主査) 教授 福原 崇介, 教授 村上 正晃, 教授 氏家 英之 |
| Degree Affiliation: | 医学院（医学専攻） |
| (Relation)haspart: | Shuai Hou, Dajun Qu, Yue Li, Baohui Zhu, Dapeng Liang, Xinyue Wei, Wei Tang, Qian Zhang, Jiaojiao Hao, Wei Guo, Weijie Wang, Siqi Zhao, Qi Wang, Sikandar Azam, Misbah Khan, Haidong Zhao, Liye Zhang, and Haixin Lei. XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence. Nucleic Acids Research, 2019 Sep 5; 47(15): 8239–8254. | | Sikandar Azam, Shuai Hou, Baohui Zhu, Weijie Wang, Tian Hao, Xiangxue Bu, Misbah Khan, and Haixin Lei. Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus. RNA Biology, 2019; 16(8): 1001–1009. | | Ji-Seung Yoo, Michihito Sasaki, Steven X Cho, Yusuke Kasuga, Baohui Zhu, Ryota Ouda,Yasuko Orba, Paul de Figueiredo, Hirofumi Sawa, Koichi S Kobayashi. SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Nature Communication, 2021 Nov 15;12(1):6602. | | Yusuke Kasuga, Baohui Zhu, Kyoung-Jin Jang, Ji-Seung Yoo. Innate immune sensing of coronavirus and viral evasion strategies. Experimental & molecular medicine, 2021 May;53(5):723-736. | | Baohui Zhu, Ryota Ouda, Paul de Figueiredo, Koichi S. Kobayashi. ORF6, a repressor of the MHC class I pathway: New molecular target for SARS-CoV-2 drug discovery? Expert Opinion on Therapeutic Targets, under review. | | Baohui Zhu, Ryota Ouda, Ning An, Koichi Kobayashi. The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation. Journal of Biological Chemistry, under review. | | Baohui Zhu. SARS-CoV-2 immune evasion mechanism by targeting MHC class I pathway.55th Hokkaido Summer Symposium of the Japanese Society of Virology, July 3, 2022,Sapporo, Japan. | | Baohui Zhu, Ryota Ouda, Ning An, Koichi Kobayashi. Activation of MHC class I by controlling NLRC5 nucleocytoplasmic trafficking. Japanese Society of Immunology,December 7, 2022, Kumamoto, Japan. |
| Type: | theses (doctoral) |
| URI: | http://hdl.handle.net/2115/92773 |
| Appears in Collections: | 学位論文 (Theses) > 博士 （医学）
課程博士 (Doctorate by way of Advanced Course) > 医学院(Graduate School of Medicine)
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