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Color-switching hydrogels as integrated microfluidic pressure sensors
Title: | Color-switching hydrogels as integrated microfluidic pressure sensors |
Authors: | Ducloué, Lucie Browse this author | Haque, Md. Anamul Browse this author | Goral, Martyna Browse this author | Ilyas, Muhammad Browse this author | Gong, Jian Ping Browse this author →KAKEN DB | Lindner, Anke Browse this author |
Issue Date: | 15-Mar-2024 |
Publisher: | Nature Publishing Group |
Journal Title: | Scientific Reports |
Volume: | 14 |
Issue: | 1 |
Start Page: | 6333 |
Publisher DOI: | 10.1038/s41598-024-56140-z |
Abstract: | Precisely measuring pressure in microfluidic flows is essential for flow control, fluid characterization, and monitoring, but faces specific challenges such as achieving sufficient resolution, non-invasiveness, or ease of use. Here, we demonstrate a fully integrated multiplexed optofluidic pressure sensor, entirely decoupled from the flow path, that enables local pressure measurements along any microfluidic channel without altering its flow geometry. The sensor itself relies on the compression of a soft mechano-actuated hydrogel, changing color in response to a pressure change. The hydrogel is separated from the fluid circulating in the channel by a thin membrane, allowing for the unrestricted use of different types of fluids. Imaging the gel through the transparent PDMS with a color camera provides a direct, easy, and contact-free determination of the fluid pressure at the sensing location for pressures as small as 20mbar with a resolution of around 10mbar. The sensitivity and accessible pressure range can be tuned via the mechanical properties of the sensing unit. The photonic gel can also be used to acquire 2D pressure or deformation maps, taking advantage of the fast response time and fine spatial resolution. |
Type: | article |
URI: | http://hdl.handle.net/2115/92945 |
Appears in Collections: | 生命科学院・先端生命科学研究院 (Graduate School of Life Science / Faculty of Advanced Life Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 龔 剣萍 (Gong Jian Ping)
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