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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Science / Faculty of Science >
Peer-reviewed Journal Articles, etc >
Expression of guanylyl cyclase genes in medaka hybrids (Oryzias curvinotus x Oryzias latipes).
| Title: | Expression of guanylyl cyclase genes in medaka hybrids (Oryzias curvinotus x Oryzias latipes). |
| Authors: | Shiga, T. Browse this author | | Suzuki, N. Browse this author |
| Keywords: | Gene expression | | Heterodimer | | Hybrid | | Medaka fish | | Membrane guanylyl cyclase | | Phylogenetic tree | | RACE | | RT-PCR | | Soluble guanylyl cyclase | | Transcription factor |
| Issue Date: | Oct-2004 |
| Publisher: | Elsevier |
| Journal Title: | Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology |
| Volume: | 139 |
| Issue: | 2 |
| Start Page: | 281 |
| End Page: | 286 |
| Publisher DOI: | 10.1016/j.cbpc.2004.08.001 |
| PMID: | 15465675 |
| Abstract: | The Hong Kong-originated medaka fish Oryzias curvinotus expresses nine genes (OcGC1～OcGC8 and OcGC-R2) for membrane guanylyl cyclases (membrane GCs) and three genes (OcGCS-α1, OcGCS-α2, and OcGCS-β1) for soluble GC subunits. The deduced amino acid sequences of membrane GCs expressed in O. curvinotus were quite similar to those expressed in the Japanese medaka Oryzias latipes, including a novel membrane GC gene, OlGC8, first isolated and characterized in O. latipes. O. curvinotus was able to produce hybrids with O. latipes, irrespective of the direction of crossing, and the resulting hybrids expressed both maternal and paternal soluble GC subunit genes, suggesting the possibility of the formation of a chimeric heterodimer in the hybrids. However, in early embryogenesis of hybrids, the maternal soluble GC subunit genes were expressed earlier than the paternal soluble GC subunit genes, suggesting that the maternal soluble GC subunit genes interact more effectively with maternal effector molecules such as transcription factors than with those of paternal origin. |
| Relation: | http://www.sciencedirect.com/science/journal/10964959 |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/13193 |
| Appears in Collections: | 理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 鈴木 範男
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