Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

Ohno, Yusuke; Kihara, Akio; Sano, Takamitsu; Igarashi, Yasuyuki

doi:10.1016/j.bbalip.2006.03.010


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Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

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Title:	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins
Authors:	Ohno, Yusuke Browse this author
	Kihara, Akio Browse this author →KAKEN DB
	Sano, Takamitsu Browse this author →KAKEN DB
	Igarashi, Yasuyuki Browse this author →KAKEN DB
Keywords:	DHHC cysteine-rich domain
	Palmitoylation
	Protein acyltransferase
Issue Date:	Apr-2006
Publisher:	Elsevier
Journal Title:	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Volume:	1761
Issue:	4
Start Page:	474
End Page:	483
Publisher DOI:	10.1016/j.bbalip.2006.03.010
PMID:	16647879
Abstract:	Increasing evidence indicates that DHHC cysteine-rich domain-containing proteins (DHHC proteins) are protein acyltransferases. Although multiple DHHC proteins are found in eukaryotes, characterization has been examined for only a few. Here, we have cloned all the yeast and human DHHC genes and investigated their intracellular localization and tissue-specific expression. Most DHHC proteins are localized in the ER and/or Golgi, with a few localized in the plasma membrane and one in the yeast vacuole. Human DHHC mRNAs also differ in their tissue-specific expression. These results may provide clues to aid in discovering the specific function(s) of each DHHC protein.
Relation:	http://www.sciencedirect.com/science/journal/13881981
Type:	article (author version)
URI:	http://hdl.handle.net/2115/14509
Appears in Collections:	薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 木原章雄

OAI-PMH ( junii2 , jpcoar_1.0 )

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