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Hokkaido University Collection of Scholarly and Academic Papers >
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最近登録された資料Sato, Kousuke... [et al.] (2016) An oligodeoxyribonucleotide containing 5-formyl-2′-deoxycytidine (fC) at the CpG site forms a covalent complex with DNA cytosine-5 methyltransferases (DNMTs). Bioorganic & Medicinal Chemistry Letters, 26(22): 5395-5398 5-Methylcytosine (mC) is known to induce epigenetic changes. Ten-eleven translocation (TET) enzymes ....
Miura, Naoya... [et al.] (2017) Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation. Journal of Pharmaceutical Sciences, 106(10): 3113-3119 The KALA peptide (WEAKLAKALAKALAKHLAKALAKALKA) is an amphiphilic peptide that forms an a-helical str....
Kagami, Keisuke... [et al.] (2018) Possibility of Poor Outcomes after Treatment Using Teicoplanin at the Minimum Inhibitory Concentration of > 2 mu g/mL in Methicillin-resistant Staphylococcus aureus Bacteremia. 薬学雑誌 Yakugaku zasshi（Journal of the pharmaceutical society of Japan）, 138(9): 1181-1189 Only minimal information exists regarding the treatment outcomes of patients suffering from methicil....
Nakajima, Kohei... [et al.] (2018) Changes in plasma membrane damage inducing cell death after treatment with near-infrared photoimmunotherapy. Cancer science, 109(9): 2889-2896 Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer phototherapy modality using an antibody c....
Maeda, Naoyoshi... [et al.] (2017) Therapeutic application of human leukocyte antigen-G1 improves atopic dermatitis-like skin lesions in mice. International immunopharmacology, 50: 202-207 Human leukocyte antigen (HLA)-G is an immune checkpoint molecule that plays critical roles in immune....
Hashiba, Kazuki... [et al.] (2017) pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes. Journal of controlled release, 262: 239-246 Lipid nanoparticles (LNPs) are one of the promising technologies for the in vivo delivery of short i....
Tomita, Mayu... [et al.] (2018) Anti PD-1 treatment increases [F-18]FDG uptake by cancer cells in a mouse B16F10 melanoma model. EJNMMI research, 8: 82 Background: Programmed cell death 1 (PD-1) inhibitors act as immune checkpoint inhibitors and are mo....
Sawai, Megumi... [et al.] (2017) The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways. Journal of Biological Chemistry (JBC), 292(37): 15538-15551 Differences among fatty acids (FAs) in chain length and number of double bonds create lipid diversit....
Takahashi, Miki... [et al.] (2017) Biochanin A enhances ROR gamma activity through STAT3-mediated recruitment of NCOA1. Biochemical and biophysical research communications, 489(4): 503-508 Interleukin (IL)-17-producing T cells play important roles in autoimmunity, chronic inflammation and....
Doi, Ryohei... [et al.] (2017) Nickel-catalyzed hydrocarboxylation of ynamides with CO2 and H2O : observation of unexpected regioselectivity. Chemical communications, 53(55): 7720-7723 We describe the nickel-catalyzed hydrocarboxylation of ynamides with CO2 and H2O to afford a variety....
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