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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam
| Title: | Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam |
| Authors: | Jin, Xue-Hai Browse this author | | Ishiko, Hiroaki Browse this author | | Nguyen, Thanh Ha Browse this author | | Ohguchi, Takeshi Browse this author | | Akanuma, Masataka Browse this author | | Aoki, Koki Browse this author | | Ohno, Shigeaki Browse this author |
| Keywords: | adenovirus | | conjunctivitis | | molecular epidemiology | | real-time PCR |
| Issue Date: | Dec-2006 |
| Publisher: | Elsevier Inc. |
| Journal Title: | American Journal of Ophthalmology |
| Volume: | 142 |
| Issue: | 6 |
| Start Page: | 1064 |
| End Page: | 1066 |
| Publisher DOI: | 10.1016/j.ajo.2006.07.041 |
| PMID: | 17157595 |
| Abstract: | Purpose: To investigate the serotypes of adenovirus causing conjunctivitis in Hanoi, Vietnam. Design: Clinical diagnosis of adenoviral conjunctivitis and laboratory-based experimental study. Methods: We collected 21 conjunctival swabs from 21 different patients with a clinical presentation compatible with adenoviral conjunctivitis, in Hanoi, Vietnam. Immunochromatography and real-time polymerase chain reaction (PCR) were performed to detect human adenovirus (HAdV). The sequence of PCR products was analyzed to determine the serotype of HAdV. Results: Of 21 samples, HAdV DNA was detected in 14 samples (66.7%) by real-time PCR. The serotype analysis showed HAdV-8 in 11 samples (78.6%), HAdV-3 in two samples (14.3%), and HAdV-37 in one sample (7.1%). Of 11 HAdV-8 samples, one sample (9.1%) was prototype, and the other 10 samples (90.9%) had identical nucleotide sequence and were identified as a variant of HAdV-8. |
| Relation: | http://www.sciencedirect.com/science/journal/00029394 |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/17151 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 大野 重昭
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