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Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam

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タイトル: Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam
著者: Jin, Xue-Hai 著作を一覧する
Ishiko, Hiroaki 著作を一覧する
Nguyen, Thanh Ha 著作を一覧する
Ohguchi, Takeshi 著作を一覧する
Akanuma, Masataka 著作を一覧する
Aoki, Koki 著作を一覧する
Ohno, Shigeaki 著作を一覧する
キーワード: adenovirus
molecular epidemiology
real-time PCR
発行日: 2006年12月
出版者: Elsevier Inc.
誌名: American Journal of Ophthalmology
巻: 142
号: 6
開始ページ: 1064
終了ページ: 1066
出版社 DOI: 10.1016/j.ajo.2006.07.041
抄録: Purpose: To investigate the serotypes of adenovirus causing conjunctivitis in Hanoi, Vietnam. Design: Clinical diagnosis of adenoviral conjunctivitis and laboratory-based experimental study. Methods: We collected 21 conjunctival swabs from 21 different patients with a clinical presentation compatible with adenoviral conjunctivitis, in Hanoi, Vietnam. Immunochromatography and real-time polymerase chain reaction (PCR) were performed to detect human adenovirus (HAdV). The sequence of PCR products was analyzed to determine the serotype of HAdV. Results: Of 21 samples, HAdV DNA was detected in 14 samples (66.7%) by real-time PCR. The serotype analysis showed HAdV-8 in 11 samples (78.6%), HAdV-3 in two samples (14.3%), and HAdV-37 in one sample (7.1%). Of 11 HAdV-8 samples, one sample (9.1%) was prototype, and the other 10 samples (90.9%) had identical nucleotide sequence and were identified as a variant of HAdV-8.
Relation (URI):
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 大野 重昭


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