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Susceptibility to oxygen desaturation during bronchoscopy in elderly patients with pulmonary fibrosis

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Title: Susceptibility to oxygen desaturation during bronchoscopy in elderly patients with pulmonary fibrosis
Authors: Shinagawa, Naofumi Browse this author
Yamazaki, Koichi Browse this author
Kinoshita, Ichiro Browse this author
Ogura, Shigeaki Browse this author
Nishimura, Masaharu Browse this author →KAKEN DB
Keywords: Bronchoscopy
oxygen desaturation
pulmonary fibrosis
interstitial pneumonia
Issue Date: Feb-2006
Publisher: Karger
Journal Title: Respiration
Volume: 73
Issue: 1
Start Page: 90
End Page: 94
Publisher DOI: 10.1159/000088093
PMID: 16155353
Abstract: Background: Fiber-optic flexible bronchoscopy (FFB) is a frequently performed procedure for the diagnosis and treatment of pulmonary disorders. However, hypoxemia occasionally occurs during FFB. Objectives: We attempted to examine the causes of arterial oxygen desaturation during FFB. Methods: We studied 336 patients who underwent FFB without intervention between June 1, 2001 and September 30, 2002. Arterial oxygen saturation (SpO2) was continuously monitored using oximetry with a recording system. We analyzed the relationship between a reduction in SpO2 during FFB and various clinical parameters or background lung diseases. Results: Of the 336 patients, 73 (22%) had an episode of oxygen desaturation (SpO2 <90% over 10 s). Of patients over 80 years old, 55% had an episode of oxygen desaturation, which was significantly higher than 27% observed in the patients of 80 and less than 80 years old (p < 0.05). Patients with pulmonary fibrosis had a higher risk of desaturation (55%) compared to patients with other complications or patients without any complication (p < 0.05). Multivariable analysis revealed that both age and pulmonary fibrosis were independent predictors of oxygen desaturation. However, the majority of the patients (94%) did not require routine oxygen supplementation. Conclusion: Although FFB is safe and does not require oxygen supplementation in most cases, age over 80 years and pulmonary fibrosis are high risk factors for significant oxygen desaturation during FFB. Copyright © 2006 S. Karger AG, Basel
Rights: © 2006, S. Karger AG, Basel
Type: article (author version)
URI: http://hdl.handle.net/2115/17180
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 山崎 浩一

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