HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Science / Faculty of Science >
Peer-reviewed Journal Articles, etc >

Localization of mRNA Encoding Thyrotropin-Releasing Hormone Precursor in the Brain of Sockeye Salmon

Files in This Item:
15(6)19.pdf798.21 kBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/32921

Title: Localization of mRNA Encoding Thyrotropin-Releasing Hormone Precursor in the Brain of Sockeye Salmon
Authors: Ando, Hironori Browse this author
Ando, Junko Browse this author
Urano, Akihisa Browse this author
Issue Date: Dec-1998
Publisher: 日本動物学会
Journal Title: Zoological Science
Volume: 15
Issue: 6
Start Page: 945
End Page: 953
Abstract: The distribution of mRNA encoding thyrotropin-releasing hormone (TRH) precursor in the brain of sockeye salmon was studied by in situ hybridization histochemistry using digoxigenin-labeled riboprobes as a basis to investigate its physiological functions in the salmon brain. Since seasonal variation in TRH gene expression was expected in relation to smelting or maturation, fish were sampled in February and October. In both groups, TRH mRNA was widely distributed in discrete brain regions including the internal cellular layer (ICL) of the olfactory bulb, postcommissural nucleus of area ventralis telencephali (Vp), nucleus preopticus parvocellularis anterioris (PPa), nucleus preopticus magnocellularis, dorsal zone of periventricular hypothalamus (Hd), torus semicircularis, and also the motor nucleus of vagus nerve in the medulla oblongata. TRH neurons in ICL and Hd are round and small with diameters of 5-10 μm. In contrast, TRH neurons in the ventral telencephalon and the preoptic area are medium-sized (10-20 μm), and appear to have multiple processes. Most of these cells are restrictively localized along the lateral margin of the preoptic nuclei. The number of TRH neurons in Vp and PPa was smaller in February than in October, suggesting a seasonal change of TRH neurons in the preoptic area. In the medulla oblongata, a cluster of large oval-shaped cells (20-30 μm) showed signals for TRH mRNA. The present results suggest that TRH may function as a neurotransmitter or neuromodulator involved in olfactory activity and also autonomic motor integration, in addition to neurohormonal control of secretion of pituitary hormones.
Rights: (c) 日本動物学会 / 本文献の公開は著者の意思に基づくものである
Relation: http://www.bioone.org/perlserv/?request=get-archive&issn=0289-0003
Type: article
URI: http://hdl.handle.net/2115/32921
Appears in Collections:理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 浦野 明央

Export metadata:

OAI-PMH ( junii2 , jpcoar )

MathJax is now OFF:


 

 - Hokkaido University