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Hokkaido University Collection of Scholarly and Academic Papers >
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Peer-reviewed Journal Articles, etc >
A novel method for introducing a polyfluoroalkyl group into aromatic compounds
| Title: | A novel method for introducing a polyfluoroalkyl group into aromatic compounds |
| Authors: | Tahara, Ryuhei Browse this author | | Fukuhara, Tadahito Browse this author | | Hara, Shoji Browse this author →KAKEN DB |
| Keywords: | polyfluoroalkylation | | fluoro-Pummerer rearrangement | | desulfurizing-difluorination | | IF5 | | 5-(perfluoroethyl)uracil |
| Issue Date: | Sep-2011 |
| Publisher: | Elsevier B.V. |
| Journal Title: | Journal of Fluorine Chemistry |
| Volume: | 132 |
| Issue: | 9 |
| Start Page: | 579 |
| End Page: | 586 |
| Publisher DOI: | 10.1016/j.jfluchem.2011.06.006 |
| Abstract: | Introduction of a polyfluoroalkyl group into aromatic compounds was achieved by Friedel-Crafts reaction using (1-chloro-1-hydroperfluoroalkyl) sulfides 1, and the subsequent desulfurizing-difluorination of the resulting product using IF5/Et3N-nHF. Perfluoroethyl, 1,1,2,2,3,3-hexafluoropropyl, and 1,1,2,2,3,3,4,4,5,5-decafluoropentyl groups were introduced to various aromatic compounds by this method. Selective perfluoroethylation of uracil at the 5-position was also performed. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/47208 |
| Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 原 正治
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