Hokkaido University Collection of Scholarly and Academic Papers >
Faculty of Pharmaceutical Sciences >
Peer-reviewed Journal Articles, etc >
New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImN^[N]:NaO^[O], consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes
Title: | New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImN^[N]:NaO^[O], consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes |
Authors: | Kuramoto, Kazuyuki Browse this author | Tarashima, Noriko Browse this author | Hirama, Yasuyuki Browse this author | Kikuchi, Yusaku Browse this author | Minakawa, Noriaki Browse this author | Matsuda, Akira Browse this author →KAKEN DB |
Issue Date: | 14-Oct-2011 |
Publisher: | Royal Society of Chemistry |
Journal Title: | Chemical Communications |
Volume: | 47 |
Issue: | 38 |
Start Page: | 10818 |
End Page: | 10820 |
Publisher DOI: | 10.1039/C1CC13805G |
PMID: | 21863185 |
Abstract: | The new imidazopyridopyrimidine:naphthyridine base-pairing motifs, ImO^[O]:NaN^[N] and ImN^[N]:NaO^[O], were designed. Among the base pairs examined, DNA duplexes containing ImN^[N]:NaO^[O] pair(s) consisting of a DAAD:ADDA hydrogen bonding pattern (D = donor, A = acceptor) were markedly stabilized thermally and thermodynamically. |
Rights: | Chem. Commun., 2011, 47, 10818-10820 - Reproduced by permission of The Royal Society of Chemistry (RSC) |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/49777 |
Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 松田 彰
|