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TAMable tumor-associated macrophages in response to innate RNA sensing

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Title: TAMable tumor-associated macrophages in response to innate RNA sensing
Authors: Seya, Tsukasa Browse this author →KAKEN DB
Shime, Hiroaki Browse this author →KAKEN DB
Matsumoto, Misako Browse this author →KAKEN DB
Keywords: TLR3
tumor-infiltrating macrophages
Issue Date: Sep-2012
Journal Title: OncoImmunology
Volume: 1
Issue: 6
Start Page: 1000
End Page: 1001
Publisher DOI: 10.4161/onci.19894
Abstract: Antitumor effect of PolyI: C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to become an additional antitumor effector through polyI: C response.
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 瀬谷 司

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