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A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1.
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Title: | A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1. |
Authors: | Kagawa, Hiroki Browse this author | Shino, Yuka Browse this author | Kobayashi, Daigo Browse this author | Demizu, Syunsuke Browse this author | Shimada, Masumi Browse this author | Ariga, Hiroyoshi Browse this author →KAKEN DB | Kawahara, Hiroyuki Browse this author →KAKEN DB |
Issue Date: | 13-Apr-2011 |
Publisher: | PloS |
Journal Title: | PloS one |
Volume: | 6 |
Issue: | 4 |
Start Page: | e18638 |
Publisher DOI: | 10.1371/journal.pone.0018638 |
PMID: | 21533246 |
Abstract: | Patched 1 (Ptc1) is a polytopic receptor protein that is essential for growth and differentiation. Its extracellular domains accept its ligand, Sonic Hedgehog, while the function of its C-terminal intracellular domain is largely obscure. |
Rights: | http://creativecommons.org/licenses/by/3.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/53698 |
Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 有賀 寛芳
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