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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Environmental Science / Faculty of Environmental Earth Science >
Peer-reviewed Journal Articles, etc >
The DNA-based gels for oral delivery of probiotic bacteria
| Title: | The DNA-based gels for oral delivery of probiotic bacteria |
| Authors: | Jonganurakkun, Benjamas1 Browse this author | | Nodasaka, Yoshinobu Browse this author | | Sakairi, Nobuo Browse this author →KAKEN DB | | Nishi, Norio Browse this author |
| Authors(alt): | ジョンアヌラックン, ベンジャマート1 |
| Keywords: | biomaterials | | DNA | | hydrogels | | probiotic strains | | drug delivery system |
| Issue Date: | 5-Jan-2006 |
| Publisher: | WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
| Journal Title: | Macromolecular Bioscience |
| Volume: | 6 |
| Issue: | 1 |
| Start Page: | 99 |
| End Page: | 103 |
| Publisher DOI: | 10.1002/mabi.200500199 |
| PMID: | 16374776 |
| Abstract: | A single-stranded DNA readily extracted from industrial discarded salmon milt, was used to prepare hydrogels and complex gels by cross-linking with gelatin and κ-carrageenan, for the oral delivery of probiotic bacteria. The complex gels showed a higher protective capability over the hydrogels for approximately one log scale. However, the hydrogels were more stable during 4°C storage. The Lactobacillus and Lactococcus due to protection of the hydrogels could better tolerate to acid than the Bifidobacterium. Furthermore, food-graded hydrogels were prepared and optimized to a similar protective capability for future applications. |
| Description: | Published in Macromolecular Bioscience, 2006, Wiiley-VCH Verlag GmbH & Co. KGaA, Weinheim |
| Relation: | http://www.interscience.wiley.com/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/5658 |
| Appears in Collections: | 環境科学院・地球環境科学研究院 (Graduate School of Environmental Science / Faculty of Environmental Earth Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: Benjamas Jonganurakkun(ベンジャマート・ジョンアヌラックン)
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