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An instrument-free, screen-printed paper microfluidic device that enables bio and chemical sensing
This item is licensed under:Creative Commons Attribution 3.0 Unported
| Title: | An instrument-free, screen-printed paper microfluidic device that enables bio and chemical sensing |
| Authors: | Mohammadi, Saeed Browse this author | | Maeki, Masatoshi Browse this author | | Mohamadi, Reza M. Browse this author | | Ishida, Akihiko Browse this author | | Tani, Hirofumi Browse this author | | Tokeshi, Manabu Browse this author →KAKEN DB |
| Issue Date: | 2015 |
| Publisher: | Royal Society of Chemistry |
| Journal Title: | Analyst |
| Volume: | 140 |
| Issue: | 19 |
| Start Page: | 6493 |
| End Page: | 6499 |
| Publisher DOI: | 10.1039/c5an00909j |
| PMID: | 26207925 |
| Abstract: | This paper describes a simple and instrument-free screen-printing method to fabricate hydrophilic channels by patterning polydimethylsiloxane (PDMS) onto chromatography paper. Clearly recognizable border lines were formed between hydrophilic and hydrophobic areas. The minimum width of the printed channel to deliver an aqueous sample was 600 mu m, as obtained by this method. Fabricated microfluidic paper-based analytical devices (mu PADs) were tested for several colorimetric assays of pH, glucose, and protein in both buffer and artificial urine samples and results were obtained in less than 30 min. The limits of detection (LODs) for glucose and bovine serum albumin (BSA) were 5 mM and 8 mu M, respectively. Furthermore, the pH values of different solutions were visually recognised with the naked eye by using a sensitive ink. Ultimately, it is expected that this PDMS-screen-printing (PSP) methodology for mu PADs can be readily translated to other colorimetric detection and hydrophilic channels surrounded by a hydrophobic polymer can be formed to transport fluids toward target zones. |
| Rights: | http://creativecommons.org/licenses/by/3.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/60219 |
| Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 渡慶次 学
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