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Peer-reviewed Journal Articles, etc >
Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells
| Title: | Transcription of 4'-thioDNA templates to natural RNA in vitro and in mammalian cells |
| Authors: | Maruyama, Hideto Browse this author | | Furukawa, Kazuhiro Browse this author | | Kamiya, Hiroyuki Browse this author →KAKEN DB | | Minakawa, Noriaki Browse this author | | Matsuda, Akira Browse this author →KAKEN DB |
| Issue Date: | 7-May-2015 |
| Publisher: | Royal Society of Chemistry |
| Journal Title: | Chemical communications |
| Volume: | 51 |
| Issue: | 37 |
| Start Page: | 7887 |
| End Page: | 7890 |
| Publisher DOI: | 10.1039/c4cc08862j |
| PMID: | 25854199 |
| Abstract: | Synthetic chemically modified nucleic acids, which are compatible with DNA/RNA polymerases, have great potential as a genetic material for synthetic biological studies. A comprehensive analysis of the transcription of 4'-thioDNA templates to natural RNA is herein reported. The modifications of DNA with 2'-deoxy-4'-thionucleosides, so-called 4'-thioDNA, were found to act as templates for transcription with RNA polymerases both in vitro and in mammalian cells. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/60827 |
| Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 丸山 豪斗
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