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北海道大学大学院教育学研究院紀要 = Bulletin of Faculty of Education, Hokkaido University >
第125号 : 矢野德郎教授退職記念号 >


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Title: 近赤外分光法を用いた筋酸素化動態測定の意義
Other Titles: Significance of Determining Muscle Oxygenation Using Near-Infrared Spectroscopy
Authors: 尾方, 寿好1 Browse this author →KAKEN DB
Authors(alt): Ogata, Hisayoshi1
Keywords: near infrared spectroscopy
muscle oxygenation
sympathetic nerve activity
metabolic vasodilation
Issue Date: 30-Mar-2016
Publisher: 北海道大学大学院教育学研究院
Journal Title: 北海道大学大学院教育学研究院紀要
Volume: 125
Start Page: 79
End Page: 90
Abstract: Near-infrared spectroscopy (NIRS) has been widely used to investigate muscle oxygenation at rest and during exercise. Oxygenated hemoglobin concentration(HbO2)measured by NIRS reflects oxygen supply under the condition in which oxygen consumption is assumed to be constant. A decrease in HbO2 occurs in non-exercised muscle during enhancement of muscle sy mpathetic nerve activity(MSNA). On the other hand, sympathetically mediated decrease in HbO2 is suppressed in exercising muscle due to a decreased level of muscle oxygenation by muscle activity, suggesting the occurrence of functional sympatholysis. Thus, a decrease in HbO2 in non-exercised muscle can be used as an index of enhancement of MSNA. Although microneurography is a gold-standard tool to measure MSNA, there are some limitations such as the necessity for practice, vulnerability of a motion artifact and difficulty in measurements in paralyzed regions of individuals with disabilities. However, there are no such limitations in NIRS measurements. Thus, NIRS enables estimation of the behavior of MSNA under the condition in which there is much movement of the body such as in severe exercise and enables estimation of the behavior of MSNA in a paralyzed limb of an individual with spinal cord injury. Since recent advances in technology have allowed us to use lowcost and portable NIRS devices, it is expected that NIRS devices will be used as tools to detect abnormal enhancement of MSNA such as autonomic dysreflexia in individuals with spinal cord injury.
Type: bulletin (article)
Appears in Collections:北海道大学大学院教育学研究院紀要 = Bulletin of Faculty of Education, Hokkaido University > 第125号 : 矢野德郎教授退職記念号

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