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Development of a new device for artificial insemination in cynomolgus macaques


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タイトル: Development of a new device for artificial insemination in cynomolgus macaques
著者: KOYAMA, Shuzo 著作を一覧する
FUKUDA, Koji 著作を一覧する
WATANABE, Sho 著作を一覧する
KOHARA, Sakae 著作を一覧する
TSUCHIYA, Hideaki 著作を一覧する
FUKUZAKI, Koichiro 著作を一覧する
NAGANO, Masashi 著作を一覧する
UNO, Yasuhiro 著作を一覧する
HOSOI, Yoshihiko 著作を一覧する
キーワード: Artificial insemination
Cynomolgus monkey
発行日: 2016年10月
出版者: 日本繁殖生物学会
誌名: Journal of Reproduction and Development
巻: 62
号: 5
開始ページ: 527
終了ページ: 529
出版社 DOI: 10.1262/jrd.2016-045
抄録: In cynomolgus macaques, an important animal species for biomedical research, efficient reproduction has been hampered partly due to the difficulties of artificial insemination (AI) using straw tubes developed for humans or farm animals, because cynomolgus macaques have a complex cervical canal structure. In this study, taking into consideration the unique structure of the macaque cervical canal, we developed a novel device for AI, comprised of a syringe and an outer cylinder. At 24 and 48 h after using this device to inject semen into one female, viable sperm were observed in the oviduct where the sperm meets the oocytes. We then attempted AI using this new device on 10 females that were at pre-ovulation, and pregnancy was successful in three animals (30% pregnancy rate). These results show that the newly developed device can be used for AI in cynomolgus macaques.
資料タイプ: article
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 永野 昌志


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