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Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines
Title: | Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines |
Authors: | Sakaguchi, Tatsuya Browse this author | Mine, Kenta Browse this author | Kudoh, Fuki Browse this author | Kamada, Rui Browse this author | Sakaguchi, Kazuyasu Browse this author →KAKEN DB |
Issue Date: | Mar-2015 |
Publisher: | Chemical Society of Japan |
Journal Title: | Chemistry Letters |
Volume: | 44 |
Issue: | 3 |
Start Page: | 327 |
End Page: | 329 |
Publisher DOI: | 10.1246/cl.141085 |
Abstract: | The physical and chemical properties of silver nanomaterials are highly dependent on their shape and size. Recently, Ag nanoparticles have been reported to be useful for medicinal and pharmaceutical applications including anticancer activity. In this study, we showed that Ag nanoplates possess significantly higher antiproliferative activity on human promyelocytic leukemia cells, HL-60, than spherical nanoparticles. The triangular Ag nanoplates induced apoptosis in the cells and were located in the same subcellular compartment as the spherical Ag nanoparticles. |
Type: | article |
URI: | http://hdl.handle.net/2115/63556 |
Appears in Collections: | 理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 坂口 和靖
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