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Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines

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Title: Antiproliferative Activity of Silver Nanoplates on Human Promyelocytic Leukemia Cell Lines
Authors: Sakaguchi, Tatsuya Browse this author
Mine, Kenta Browse this author
Kudoh, Fuki Browse this author
Kamada, Rui Browse this author
Sakaguchi, Kazuyasu Browse this author →KAKEN DB
Issue Date: Mar-2015
Publisher: Chemical Society of Japan
Journal Title: Chemistry Letters
Volume: 44
Issue: 3
Start Page: 327
End Page: 329
Publisher DOI: 10.1246/cl.141085
Abstract: The physical and chemical properties of silver nanomaterials are highly dependent on their shape and size. Recently, Ag nanoparticles have been reported to be useful for medicinal and pharmaceutical applications including anticancer activity. In this study, we showed that Ag nanoplates possess significantly higher antiproliferative activity on human promyelocytic leukemia cells, HL-60, than spherical nanoparticles. The triangular Ag nanoplates induced apoptosis in the cells and were located in the same subcellular compartment as the spherical Ag nanoparticles.
Type: article
Appears in Collections:理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 坂口 和靖

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