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Improvement of transcutaneous fluorescent images with a depth-dependent point-spread function

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タイトル: Improvement of transcutaneous fluorescent images with a depth-dependent point-spread function
著者: Shimizu, Koichi 著作を一覧する
Koji, Tochio 著作を一覧する
Kato, Yuji 著作を一覧する
キーワード: Image processing : Deconvolution
Image processing : Image reconstruction-restoration
Medical optics and biotechnology : Image reconstruction techniques
Medical optics and biotechnology : Light propagation in tissues
Medical optics and biotechnology : Medical and biological imaging
Medical optics and biotechnology : Turbid media
scattering
fluorescence
imaging
molecular imaging
transillumination imaging
PSF
発行日: 2005年 4月
出版者: Optical Society of America
誌名: Applied Optics
巻: 44
号: 11
開始ページ: 2154
終了ページ: 2161
抄録: The point-spread function (PSF) for transcutaneous fluorescent imaging was obtained as an analytical solution in a closed form. It is applicable to cases in which the optical property of the image-blurring turbid medium is considered to be fairly homogeneous. We proposed a technique to improve a transcutaneous image by using depth-dependent PSF. Contrast of the fluorescent image was improved for depths of 1-15 mm in a scattering medium (µ_s' = 1/mm). The visible depth was more than doubled with this technique. An experiment with a rat demonstrated considerable improvement of a transcutaneous image of the cerebral vein at a specified depth. The spread image of the heart was reduced to the correct size by use of the PSF with the actual depth of the heart.
Rights: (c) 2005 Optical Society of America
Relation (URI): http://ao.osa.org/journal/ao/about.cfm
http://ao.osa.org/abstract.cfm?id=83251
資料タイプ: article
URI: http://hdl.handle.net/2115/643
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 清水 孝一

 

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