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Detection and measurement of rheumatoid bone and joint lesions of fingers by tomosynthesis: a phantom study for reconstruction filter setting optimization

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/64397

Title: Detection and measurement of rheumatoid bone and joint lesions of fingers by tomosynthesis: a phantom study for reconstruction filter setting optimization
Authors: Ono, Yohei Browse this author
Kamishima, Tamotsu Browse this author →KAKEN DB
Yasojima, Nobutoshi Browse this author
Tamura, Kenichi Browse this author
Tsutsumi, Kaori Browse this author →KAKEN DB
Keywords: Tomosynthesis
Bone erosion
Joint space narrowing
Bone phantom
Reconstruction filter
Issue Date: Jan-2016
Publisher: Springer
Journal Title: Radiological Physics and Technology
Volume: 9
Issue: 1
Start Page: 6
End Page: 14
Publisher DOI: 10.1007/s12194-015-0327-0
PMID: 26092218
Abstract: Rheumatoid arthritis (RA) is a systemic disease that is caused by autoimmunity. RA causes synovial proliferation, which may result in bone erosion and joint space narrowing in the affected joint. Tomosynthesis is a promising modality which may detect early bone lesions such as small bone erosion and slight joint space narrowing. Nevertheless, so far, the optimal reconstruction filter for detection of early bone lesions of fingers on tomosynthesis has not yet been known. Our purpose in this study was to determine an optimal reconstruction filter setting by using a bone phantom. We obtained images of a cylindrical phantom with holes simulating bone erosions (diameters of 0.6, 0.8, 1.0, 1.2, and 1.4 mm) and joint spaces by aligning two phantoms (space widths from 0.5 to 5.0 mm with 0.5 mm intervals), examining six reconstruction filters by using tomosynthesis. We carried out an accuracy test of the bone erosion size and joint space width, done by one radiological technologist, and a test to assess the visibility of bone erosion, done by five radiological technologists. No statistically significant difference was observed in the measured bone erosion size and joint space width among all of the reconstruction filters. In the visibility assessment test, reconstruction filters of Thickness+− and Thickness−− were among the best statistically in all characteristics except the signal-to-noise ratio. The Thickness+− and Thickness−− reconstruction filter may be optimal for evaluation of RA bone lesions of small joints in tomosynthesis.
Rights: The final publication is available at Springer via http://dx.doi.org/10.1007/s12194-015-0327-0.
Type: article (author version)
URI: http://hdl.handle.net/2115/64397
Appears in Collections:保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 神島 保

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