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Efficient Synthesis of Photoreactive 2-Propoxyaniline Derivatives as Artificial Sweeteners

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Title: Efficient Synthesis of Photoreactive 2-Propoxyaniline Derivatives as Artificial Sweeteners
Authors: Hashimoto, Makoto Browse this author →KAKEN DB
Murai, Yuta Browse this author
Yoshida, Takuma Browse this author
Wang, Lei Browse this author
Masuda, Katsuyoshi Browse this author
Hashidoko, Yasuyuki Browse this author →KAKEN DB
Monde, Kenji Browse this author
Hatanaka, Yasumaru Browse this author
Keywords: photoaffinity labeling
chemical biology
artificial sweetener
sweet receptor
Issue Date: Apr-2016
Publisher: Thieme
Journal Title: Synlett
Volume: 27
Issue: 06
Start Page: 946
End Page: 950
Publisher DOI: 10.1055/s-0035-1561275
Abstract: 5-Nitro-2-propoxyaniline is one of the strongest artificial sweeteners. However, little is known about the detailed relationship of the structure and biological activity between 5-nitro-2-propoxyaniline and its sweet receptor. Photoaffinity labeling is a useful method for revealing interactions of a small bioactive compound with molecules. Therefore, we synthesized photoreactive 2-propoxyaniline derivatives as useful tools for revealing the interactions by photoaffinity labeling.
Rights: これは出版社に投稿した著者最終原稿です。This is the accepted manuscript.
Type: article (author version)
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 橋本 誠

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