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Hokkaido University Collection of Scholarly and Academic Papers >
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Stereoretentive Addition of N-tert-Butylsulfonyl-alpha-Amido Silanes to Aldehydes, Ketones, alpha,beta-Unsaturated Esters, and Imines
| Title: | Stereoretentive Addition of N-tert-Butylsulfonyl-alpha-Amido Silanes to Aldehydes, Ketones, alpha,beta-Unsaturated Esters, and Imines |
| Authors: | Mita, Tsuyoshi Browse this author →KAKEN DB | | Saito, Keisuke Browse this author | | Sugawara, Masumi Browse this author | | Sato, Yoshihiro Browse this author →KAKEN DB |
| Keywords: | aldehydes | | cesium fluoride | | ketones | | silanes | | stereospecific reactions |
| Issue Date: | 20-May-2016 |
| Publisher: | Wiley-Blackwell |
| Journal Title: | Chemistry-an asian journal |
| Volume: | 11 |
| Issue: | 10 |
| Start Page: | 1528 |
| End Page: | 1531 |
| Publisher DOI: | 10.1002/asia.201600270 |
| PMID: | 27027853 |
| Abstract: | Enantioenriched N-tert-butylsulfonyl-alpha-amido si-lanes were successfully reacted with aldehydes, ketones, imines, and alpha,beta-unsaturated esters in the presence of a sub-stoichiometric amount of CsF (0.5 equiv) in 1,2-di-methoxyethane (DME) at -20 degrees C to afford the corresponding coupling products with up to 89% enantiospecificity in a retentive manner. |
| Rights: | This is the accepted version of the following article: T. Mita, K. Saito, M. Sugawara, Y. Sato, Chem. Asian J. 2016, 11, 1528., which has been published in final form at http://dx.doi.org/10.1002/asia.201600270. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy http://olabout.wiley.com/WileyCDA/Section/id-828039.html |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/65507 |
| Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 美多 剛
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