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Solid-Phase Modular Synthesis of Park Nucleotide and Lipids I and II Analogues

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Title: Solid-Phase Modular Synthesis of Park Nucleotide and Lipids I and II Analogues
Authors: Katsuyama, Akira Browse this author
Sato, Kousuke Browse this author
Yakushiji, Fumika Browse this author
Matsumaru, Takanori Browse this author
Ichikawa, Satoshi Browse this author →KAKEN DB
Keywords: peptidoglycan
natural product
solid-phase synthesis
Issue Date: Jan-2018
Publisher: The Pharmaceutical Society of Japan
Journal Title: Chemical & pharmaceutical bulletin
Volume: 66
Issue: 1
Start Page: 84
End Page: 95
Publisher DOI: 10.1248/cpb.c17-00828
PMID: 29311516
Abstract: A solid-phase synthesis of Park nucleotide as well as lipids I and II analogues, which is applicable to the synthesis of a range of analogues, is described in this work. This technique allows highly functionalized macromolecules to be modularly labeled. Multiple steps are used in a short time (4d) with a single purification step to synthesize the molecules by solid-phase synthesis.
Type: article
Appears in Collections:薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 市川 聡

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