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Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report
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| Title: | Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report |
| Authors: | Kuwabara, Shota Browse this author | | Ebihara, Yuma Browse this author →KAKEN DB | | Nakanishi, Yoshitsugu Browse this author | | Asano, Toshimichi Browse this author | | Noji, Takehiro Browse this author →KAKEN DB | | Kurashima, Yo Browse this author →KAKEN DB | | Murakami, Soichi Browse this author | | Nakamura, Toru Browse this author →KAKEN DB | | Tsuchikawa, Takahiro Browse this author →KAKEN DB | | Okamura, Keisuke Browse this author | | Shichinohe, Toshiaki Browse this author →KAKEN DB | | Hirano, Satoshi Browse this author →KAKEN DB |
| Keywords: | Esophagus | | Melanoma | | Pathology | | Treatment | | Prognosis |
| Issue Date: | 2-Dec-2017 |
| Publisher: | BioMed Central |
| Journal Title: | BMC surgery |
| Volume: | 17 |
| Start Page: | 122 |
| Publisher DOI: | 10.1186/s12893-017-0326-7 |
| Abstract: | Background: Primary malignant melanoma of the esophagus (PMME) is a rare disease with a poor prognosis. There are few reports of early-stage cases in which tumor invasion reached the lamina propria or muscularis mucosae, as in the present case. A standard treatment for early-stage PMME has not yet been established. The present study aimed to summarize previous reports and to discuss the indications for surgical treatment of early-stage primary malignant melanoma of the esophagus. Case presentation: A 70-year-old woman with PMME was referred to our hospital. She underwent thoracoscopic and laparoscopic subtotal esophagectomy with lymphadenectomy. The resected specimen showed melanocytosis and junctional activity. Melanoma-specific antigens melan-A, S-100, and HMB45 were detected by immunohistochemical staining. The pathological diagnosis was pT1a-MM, pN0, pM0, and pStage IA. She remains alive without evidence of recurrence 39 months later. Conclusion: Subtotal esophagectomy with regional radical lymphadenectomy could be recommended to patients with early-stage primary malignant melanoma of the esophagus, and curative surgical resection could improve their prognosis. |
| Rights: | http://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/68335 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 海老原 裕磨
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