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Characteristics of Microfluidic Paper-based Analytical Devices Fabricated by Four Different Methods

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タイトル: Characteristics of Microfluidic Paper-based Analytical Devices Fabricated by Four Different Methods
著者: Komatsu, Takeshi 著作を一覧する
Maeki, Masatoshi 著作を一覧する
Ishida, Akihiko 著作を一覧する
Tani, Hirofumi 著作を一覧する
Tokeshi, Manabu 著作を一覧する
キーワード: Paper-based analytical devices
wax printing
screen printing
craft cutting
発行日: 2018年 1月
出版者: 日本分析化学会(Japan Society for Analytical Chemistry)
誌名: Analytical sciences
巻: 34
号: 1
開始ページ: 39
終了ページ: 44
出版社 DOI: 10.2116/analsci.34.39
抄録: We report on the effects of fabrication methods, photolithography, wax printing, screen printing, and craft cutting, on selected properties of microfluidic paper-based analytical devices (mu PADs): cost, fabrication precision, wicking rate, and analytical accuracy. Photolithography requires numerous fabrication steps, and an oxygen plasma treatment is necessary when using an aqueous solution. Although the boundary between the hydrophobic and hydrophilic areas in the mu PAD is sharpest, the obtained K-scale intensity in measuring of protein concentrations is lower than those of the devices by other methods. Wax printing offers the simplest and fastest fabrication, although solution leakage measures should be taken to improve the wicking rate and to prevent cross-contamination. Screen printing also offers easy fabrication. The screen printed mu PAD has a good wicking performance and shows a high detection intensity. Craft cutting allows automated fabrication of many mu PADs at once. The craft cut mu PAD has the fastest wicking rate among the four mu PADs due to bare cellulose fibers. We consider that the detection intensity of this mu PAD can be raised by optimizing the evaporation rate.
資料タイプ: article
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 渡慶次 学


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